Evidence map›Paper›PMID 32733485›Full record

ArticleFrontiers in immunology2020

Type I Interferon Regulates the Survival and Functionality of B Cells in Rainbow Trout.

Ottavia Benedicenti, Tiehui Wang, Esther Morel, Christopher J Secombes, Irene Soleto, Patricia Díaz-Rosales, Carolina Tafalla

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ottavia BenedicentiAnimal Health Research Center (CISA-INIA), Madrid, Spain.
Tiehui WangScottish Fish Immunology Research Centre, School of Biological Sciences, University of Aberdeen, Aberdeen, United Kingdom.
Esther MorelAnimal Health Research Center (CISA-INIA), Madrid, Spain.
Christopher J SecombesScottish Fish Immunology Research Centre, School of Biological Sciences, University of Aberdeen, Aberdeen, United Kingdom.
Irene SoletoAnimal Health Research Center (CISA-INIA), Madrid, Spain.
Patricia Díaz-RosalesAnimal Health Research Center (CISA-INIA), Madrid, Spain.
Carolina TafallaAnimal Health Research Center (CISA-INIA), Madrid, Spain.
University of Aberdeen · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interferons (IFNs) orchestrate antiviral responses in jawed vertebrates and can be classified into three types based on different aspects of their genomic organization, structure and receptors through which they signal and function. Generally, type I and type III IFNs include cytokines that directly induce an antiviral response, whereas type II IFNs are well-known for their immunomodulatory role during viral infections. In mammals, type I IFNs have been shown to also regulate many aspects of B cell development and differentiation. Yet, these functions have been only faintly investigated for teleost IFNs. Thus, in the current study, we have examined the effects of a model type I rainbow trout IFN molecule (IFNa) on blood naïve (IgM

Indexed as

AnimalsB-LymphocytesCell DifferentiationCells, CulturedCell SurvivalFish ProteinsGene Expression RegulationHumansImmunoglobulin MInterferon Type ILymphocyte ActivationMammalsOncorhynchus mykissPhagocytosisFish ProteinsImmunoglobulin MInterferon Type Isecretory IgMB cellsIgMinterferon (IFN)phagocytosisteleost fish

Identifiers

PMID32733485
PMCPMC7363951
OpenAlexW3041875777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.