Evidence map›Paper›PMID 32733440›Full record

ArticleFrontiers in immunology2020

Extracellular AMP Suppresses Endotoxemia-Induced Inflammation by Alleviating Neutrophil Activation.

Ye Hua, Dadong Liu, Danyi Zhang, Xu Wang, Qing Wei, Weiting Qin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Extracellular AMP Inhibits Pollen Tube Growth inPlants (Basel, Switzerland) · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Exploring the Muscle Metabolomics in the Mouse Model of Sepsis-Induced Acquired Weakness.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ye HuaInstitute of Oncology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Dadong LiuDepartment of ICU, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Danyi ZhangDepartment of Laboratory Medicine, Affiliated People's Hospital Jiangsu University Zhenjiang, Zhenjiang, China.
Xu WangInstitute of Oncology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Qing WeiDepartment of General Surgery, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Weiting QinState Key Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute Shanghai Jiao Tong University, Shanghai, China.
Jiangsu University · CNAffiliated Hospital of Jiangsu University · CNShanghai Cancer Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracellular adenosine monophosphate (AMP) is indispensable for cellular metabolic processes, and it is interconverted to ADP and/or ATP or activates AMP-activated protein kinase (AMPK). However, the specific biological function of extracellular AMP has not been identified. We evaluated the effect of extracellular AMP using

Indexed as

Adenosine MonophosphateAnimalsApoptosisCell AdhesionDisease Models, AnimalEndotoxemiaExtracellular SpaceHumansImmunophenotypingLipopolysaccharidesMaleMiceNeutrophil ActivationNeutrophil InfiltrationNeutrophilsp38 Mitogen-Activated Protein KinasesAdenosine MonophosphateLipopolysaccharidesp38 Mitogen-Activated Protein KinasesReactive Oxygen SpeciesReceptors, Purinergic P1A1RAMPendotoxemianeutrophilsp38 MAPK

Identifiers

PMID32733440
PMCPMC7358592
OpenAlexW3040426811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.