Evidence map›Paper›PMID 32733428›Full record

ArticleFrontiers in microbiology2020

Mobility of β-Lactam Resistance Under Bacterial Co-infection and Ampicillin Treatment in a Mouse Model.

Alexander Laskey, Marie Ottenbrite, John Devenish, Mingsong Kang, Mirjana Savic, Susan Nadin-Davis, John Chmara, Min Lin, James Robertson, Kyrylo Bessonov and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Antimicrobial agents and chemotherapy · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Mobility ofMicrobial genomics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Alexander LaskeyOttawa Laboratory, Fallowfield, Canadian Food Inspection Agency, Ottawa, ON, Canada.
Marie OttenbriteOttawa Laboratory, Fallowfield, Canadian Food Inspection Agency, Ottawa, ON, Canada.
John DevenishOttawa Laboratory, Fallowfield, Canadian Food Inspection Agency, Ottawa, ON, Canada.
Mingsong KangOttawa Laboratory, Fallowfield, Canadian Food Inspection Agency, Ottawa, ON, Canada.
Mirjana SavicOttawa Laboratory, Fallowfield, Canadian Food Inspection Agency, Ottawa, ON, Canada.
Susan Nadin-DavisOttawa Laboratory, Fallowfield, Canadian Food Inspection Agency, Ottawa, ON, Canada.
John ChmaraOttawa Laboratory, Fallowfield, Canadian Food Inspection Agency, Ottawa, ON, Canada.
Min LinOttawa Laboratory, Fallowfield, Canadian Food Inspection Agency, Ottawa, ON, Canada.
James RobertsonNational Microbiology Laboratory, Public Health Agency of Canada, Guelph, ON, Canada.
Kyrylo BessonovNational Microbiology Laboratory, Public Health Agency of Canada, Guelph, ON, Canada.
Simone GurnikNational Microbiology Laboratory, Public Health Agency of Canada, Guelph, ON, Canada.
Kira LiuNational Microbiology Laboratory, Public Health Agency of Canada, Guelph, ON, Canada.
John H E NashNational Microbiology Laboratory, Public Health Agency of Canada, Guelph, ON, Canada.
Andrew ScottLondon Research and Development Centre, Agriculture and Agri-Food Canada, London, ON, Canada.
Edward ToppLondon Research and Development Centre, Agriculture and Agri-Food Canada, London, ON, Canada.
Jiewen GuanOttawa Laboratory, Fallowfield, Canadian Food Inspection Agency, Ottawa, ON, Canada.
Canadian Food Inspection Agency · CAPublic Health Agency of Canada · CAAgriculture and Agri-Food Canada · CALondon Research and Development Centre

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ingestion of food- or waterborne antibiotic-resistant bacteria may lead to the dissemination of antibiotic-resistance genes in the gut microbiota and the development of antibiotic-resistant bacterial infection, a significant threat to animal and public health. Food or water may be contaminated with multiple resistant bacteria, but animal models on gene transfer were mainly based on single-strain infections. In this study, we investigated the mobility of β-lactam resistance following infection with single- versus multi-strain of resistant bacteria under ampicillin treatment. We characterized three bacterial strains isolated from food-animal production systems,

Indexed as

antibiotic resistanceantibiotic treatmentgut microbiotaintestinal inflammationplasmid transfer

Identifiers

PMID32733428
PMCPMC7358583
OpenAlexW3040948319

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.