ArticleFrontiers in neurology2020
Tuberous Sclerosis Complex-Associated Neuropsychiatric Disorders (TAND): New Findings on Age, Sex, and Genotype in Relation to Intellectual Phenotype.
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In one paragraph
Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 14% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Tuberous sclerosis-associated psychosis: a systematic review.Journal of neural transmission (Vienna, Austria : 1996) · 2026Pooled it
- Burden of illness in tuberous sclerosis complex-associated epilepsy: a systematic literature review of epidemiology, health-related quality of life, costs and resource use.Orphanet journal of rare diseases · 2025Pooled it
- Translational dysregulation as a mechanistic driver of cognitive, behavioral, and affective phenotypes in FXS and TSC.Neuroscience and biobehavioral reviews · 2026Review
- The interactions between sleep difficulties and clinical features in children with rare genetic syndromes: a structural equation modelling approach.BMC pediatrics · 2026Article
- Closing the Gap to Interventions for Tuberous Sclerosis Complex-Associated Neuropsychiatric Disorders (TAND): Protocol for a Longitudinal Study of TAND Severity, Predictors, and Caregiver Well-Being (TANDem-2).JMIR research protocols · 2026Article
- Autism Spectrum Disorder Symptom Profiles in Fragile X Syndrome, Angelman Syndrome, Tuberous Sclerosis Complex and Neurofibromatosis Type 1.Journal of autism and developmental disorders · 2026Article
- Deep developmental phenotyping in children with tuberous sclerosis complex, with and without autism.Developmental medicine and child neurology · 2025Article
- Genetic screening of tuberous sclerosis complex in Sicily with a focus on neurological manifestations.Scientific reports · 2025Article
- Neuropsychiatric manifestations of tuberous sclerosis in a young man in a psychiatric hospital in Botswana: a case report.The Journal of international medical research · 2024Article
- International consensus recommendations for the identification and treatment of tuberous sclerosis complex-associated neuropsychiatric disorders (TAND).Journal of neurodevelopmental disorders · 2023Article
- De novo mutation of the TSC2 gene in patient with Tuberous Sclerosis Complex-Associated Neuropsychiatric Disorders (TAND) Phenotype: a case report.Annals of medicine and surgery (2012) · 2023Article
- Tuberous Sclerosis Complex Patients' Needs and Difficulties-Results of TAND Questionnaire Analysis in Polish Adult Population.Journal of clinical medicine · 2022Article
- Tuberous sclerosis complex is a novel, amyloid-independent tauopathy associated with elevated phosphorylated 3R/4R tau aggregation.Acta neuropathologica communications · 2022Article
- Symptom rates and profile clustering in tuberous sclerosis complex-associated neuropsychiatric disorders (TAND).Journal of neurodevelopmental disorders · 2021Article
- EWAS of Monozygotic Twins Implicate a Role of mTOR Pathway in Pathogenesis of Tic Spectrum Disorder.Genes · 2021Article
- A comparison of two studies and the prevalence and sex ratio of Neurodevelopmental conditions in Tuberous Sclerosis Complex.Orphanet journal of rare diseases · 2021Article
- Dopaminergic Dysregulation in Syndromic Autism Spectrum Disorders: Insights From Genetic Mouse Models.Frontiers in neural circuits · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors at 20 institutions in 19 countries.
Petrus J de VriesDivision of Child and Adolescent Psychiatry, University of Cape Town, Cape Town, South Africa.
Elena BelousovaResearch and Clinical Institute of Pediatrics, Pirogov Russian National Research Medical University, Moscow, Russia.
Mirjana P BenedikSPS Pediatrična Klinika, Ljubljana, Slovenia.
Tom CarterTSA Tuberous Sclerosis Association, Nottingham, United Kingdom.
Vincent CottinHôpital Louis Pradel, Claude Bernard University Lyon 1, Lyon, France.
Paolo CuratoloTor Vergata University Hospital, Rome, Italy.
Maria DahlinAstrid Lindgren Childrens Hospital, Stockholm, Sweden.
Lisa D'AmatoNovartis Farma S.p.A., Origgio, Italy.
Guillaume Beaure d'AugèresAssociation Sclérose Tubéreuse de Bourneville, Gradignan, France.
José C FerreiraCentro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
Martha FeuchtUniversitätsklinik für Kinder-und Jugendheilkunde, Affiliated Partner of the ERN EpiCARE, Vienna, Austria.
Carla FladrowskiAssociazione Sclerosi Tuberosa ONLUS, Milan, Italy.
Christoph HertzbergVivantes-Klinikum Neukölln, Berlin, Germany.
Sergiusz JozwiakDepartment of Child Neurology, Medical University of Warsaw, Warsaw, Poland.
John A LawsonThe Tuberous Sclerosis Multidisciplinary Management Clinic, Sydney Children's Hospital, Randwick, NSW, Australia.
Alfons MacayaHospital Universitari Vall d'Hebron, Barcelona, Spain.
Ruben MarquesNovartis Farma S.p.A., Origgio, Italy.
Rima NabboutDepartment of Pediatric Neurology, Necker Enfants Malades Hospital, Paris Descartes University, Paris, France.
Finbar O'CallaghanClinical Neurosciences Section, Institute of Child Health, University College London, London, United Kingdom.
Jiong QinDepartment of Pediatrics, Peking University People's Hospital (PKUPH), Beijing, China.
Valentin SanderTallinn Children Hospital, Tallinn, Estonia.
Matthias SauterKlinikverbund Kempten-Oberallgäu gGmbH, Kempten, Germany.
Seema ShahNovartis Healthcare Pvt. Ltd., Hyderabad, India.
Yukitoshi TakahashiNational Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, NHO, Shizuoka, Japan.
Renaud TouraineDepartment of Genetics, CHU-Hôpital Nord, Saint-Étienne, France.
Sotiris YouroukosSt. Sophia Children's Hospital, Athens, Greece.
Bernard ZonnenbergUniversity Medical Center, Utrecht, Netherlands.
John C KingswoodCardiology Clinical Academic Group, Molecular and Clinical Sciences Research Centre, St Georges University of London, London, United Kingdom.
Anna C JansenPediatric Neurology Unit, Department of Pediatrics, UZ Brussel VUB, Brussels, Belgium.
TOSCA Investigators
Novartis (Italy) · ITAssociazione Italiana Sclerosi Multipla · ITCentro Hospitalar de Lisboa Ocidental · PTChildren's Hospital Agia Sophia · GRChildren's Memorial Health Institute · PLHôpital Louis Pradel · FRHôpital Necker-Enfants Malades · FRHôpital Nord · FRKempten University of Applied Sciences · DENational Epilepsy Center · JPNovartis (India) · INOčesna Klinika UKC Ljubljana · SIPeking University · CNPirogov Russian National Research Medical University · RUQueen Astrid Military Hospital · BESt George's, University of London · GBSydney Children's Hospital · AUTallinn Health Care College · EETuberous Sclerosis Association · GBUniversitair Ziekenhuis Brussel · BE
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
intelligence quotientTAND profileTOSCATSC-associated neuropsychiatric disorderstuberous sclerosis complex
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.