Evidence map›Paper›PMID 32733229›Full record

ArticleFrontiers in synaptic neuroscience2020

Dendritic and Spine Heterogeneity of von Economo Neurons in the Human Cingulate Cortex.

Nivaldo D Correa-Júnior, Josué Renner, Francisco Fuentealba-Villarroel, Arlete Hilbig, Alberto A Rasia-Filho

Open access · goldAbstract read
In one paragraph

Article in Frontiers in synaptic neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Introduction: What Are Dendritic Spines?Advances in neurobiology · 2023
    Article
  4. Review
  5. Article
  6. The Subcortical-Allocortical- NeocorticalFrontiers in synaptic neuroscience · 2021
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nivaldo D Correa-JúniorGraduate Program in Biosciences, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brazil.
Josué RennerLaboratory of Morphology and Physiology, Department of Basic Sciences/Physiology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
Francisco Fuentealba-VillarroelGraduate Program in Neuroscience, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Arlete HilbigDepartment of Medical Clinics/Neurology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
Alberto A Rasia-FilhoGraduate Program in Biosciences, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brazil.
Universidade Federal de Ciências da Saúde de Porto Alegre · BRUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human cingulate cortex (CC), included in the paralimbic cortex, participates in emotion, visceral responses, attention, cognition, and social behaviors. The CC has spindle-shaped/fusiform cell body neurons in its layer V, the von Economo neurons (VENs). VENs have further developed in primates, and the characterization of human VENs can benefit from the detailed descriptions of the shape of dendrites and spines. Here, we advance this issue and studied VENs in the anterior and midcingulate cortex from four neurologically normal adult subjects. We used the thionin technique and the adapted "single-section" Golgi method for light microscopy. Three-dimensional (3D) reconstructions were carried out for the visualization of Golgi-impregnated VENs' cell body, ascending and descending dendrites, and collateral branches. We also looked for the presence, density, and shape of spines from proximal to distal dendrites. These neurons have a similar aspect for the soma, but features of spiny dendrites evidenced a morphological heterogeneity of CC VENs. Only for the description of this

Indexed as

3D reconstructiondendritic spinesGolgi methodhuman brain/cytologymodified pyramidal neuronsneocortical layer Vparalimbic cortex

Identifiers

PMID32733229
PMCPMC7360805
OpenAlexW3040227845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.