Evidence map›Paper›PMID 32733203›Full record

ArticleFrontiers in cellular neuroscience2020

Case Report: Histopathology and Prion Protein Molecular Properties in Inherited Prion Disease With a

Ignazio Cali, Laura Cracco, Dario Saracino, Rossana Occhipinti, Cinzia Coppola, Brian Stephen Appleby, Gianfranco Puoti

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ignazio CaliDepartment of Pathology, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Laura CraccoDepartment of Pathology and Laboratory Medicine, School of Medicine, Indiana University, Indianapolis, IN, United States.
Dario SaracinoDivision of Neurology, University of Campania "Luigi Vanvitelli", Caserta, Italy.
Rossana OcchipintiDepartment of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Cinzia CoppolaDivision of Neurology, University of Campania "Luigi Vanvitelli", Caserta, Italy.
Brian Stephen ApplebyDepartment of Pathology, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Gianfranco PuotiDivision of Neurology, University of Campania "Luigi Vanvitelli", Caserta, Italy.
Case Western Reserve University · USUniversity of Campania "Luigi Vanvitelli" · ITIndiana University Indianapolis

Funding

Acid secretion and intracellular pH regulation in proximal-tubule cellsK01DK107787 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI OCCHIPINTI, ROSSANA · 2015 to 2019
$541k
NIDDK NIH HHS K01 DK107787
6 · The paper itself

Abstract

The insertion of additional 168 base pair containing seven octapeptide repeats in the prion protein (PrP) gene region spanning residues 51-91 is associated with inherited prion disease. In 2008, we reported the clinical features of a novel

Indexed as

conformationgenetichistopathologyinsertion mutationPrion protein (PrP)

Identifiers

PMID32733203
PMCPMC7362343
OpenAlexW3041292927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.