ArticleScientific reports2020
Clinical and neuroimaging factors associated with aphasia severity in stroke patients: diffusion tensor imaging study.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Prevalence of depression in post-stroke aphasia: systematic review and meta-analysis.BMC neurology · 2025Pooled it
- Meta-analysis and systematic review of the relationship between sex and the risk or incidence of poststroke aphasia and its types.BMC geriatrics · 2024Pooled it
- Revealing the Neuroimaging Mechanism of Acupuncture for Poststroke Aphasia: A Systematic Review.Neural plasticity · 2022Pooled it
- Microstructural properties in subacute aphasia: concurrent and prospective relationships underpinning recovery.Brain structure & function · 2024Trial
- Diffusion Tensor Imaging and Advanced Diffusion Imaging in Post-Stroke Aphasia Recovery.Tomography (Ann Arbor, Mich.) · 2026Review
- Explainable artificial intelligence on safe balance and its major determinants in stroke patients.Scientific reports · 2024Article
- Predicting Language Function Post-Stroke: A Model-Based Structural Connectivity Approach.Neurorehabilitation and neural repair · 2024Article
- Application study of DTI combined with ASL in the crossed cerebellar diaschisis after subacute cerebral hemorrhage.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- White matter microstructural integrity pre- and post-treatment in individuals with chronic post-stroke aphasia.Brain and language · 2022Article
- The Recovery Mechanism of Standardized Aphasia in Intelligent Medical Treatment.Contrast media & molecular imaging · 2022Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated factors associated with aphasia severity at both 2 weeks and 3 months after stroke using demographic and clinical variables, brain diffusion tensor imaging (DTI) parameters, and lesion volume measurements. Patients with left hemisphere stroke were assessed at 2 weeks (n = 68) and at 3 months (n = 20) after stroke. Demographic, clinical, and neuroimaging data were collected; language functions were assessed using the Western Aphasia Battery. For neuroimaging, DTI parameters, including the laterality index (LI) of fractional anisotropy (FA), axial diffusivity (AD), radial diffusivity, mean diffusivity and fibre density (FD) of the arcuate fasciculus (AF), and lesion volume, were measured. Lesion volume, cortical involvement, and the National Institutes of Health Stroke Scale score significantly predicted aphasia severity at 2 weeks after stroke, whereas the aphasia quotient and presence of depression during the early subacute stage were significant predictors at 3 months after stroke. According to Pearson correlation, LI-AD and LI-FD were significantly correlated with the aphasia quotient 2 weeks after ischaemic stroke, and the LI-FA was significantly correlated with the aphasia quotient 2 weeks after haemorrhagic stroke, suggesting that the extent and mechanism of AF injuries differ between ischaemic and haemorrhagic strokes. These differences may contribute to aphasia severity.
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