Evidence map›Paper›PMID 32732431›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

REM sleep stabilizes hypothalamic representation of feeding behavior.

Lukas T Oesch, Mary Gazea, Thomas C Gent, Mojtaba Bandarabadi, Carolina Gutierrez Herrera, Antoine R Adamantidis

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Brain Nutrient Sensing: A Unifying Framework.Annual review of physiology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Reciprocal Lateral Hypothalamic and Raphe GABAergic Projections Promote Wakefulness.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  8. Cell-Type-Specific Dynamics of Calcium Activity in Cortical Circuits over the Course of Slow-Wave Sleep and Rapid Eye Movement Sleep.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  9. Mapping Network Activity in Sleep.Frontiers in neuroscience · 2021
    Review
  10. Peripheral Lipopolyssacharide Rapidly Silences REM-Active LHFrontiers in behavioral neuroscience · 2021
    Article
  11. REM sleep stabilizes hypothalamic representation of feeding behavior.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lukas T OeschZentrum für Experimentelle Neurologie, Department of Neurology, Inselspital University Hospital Bern, CH-3010 Bern, Switzerland.ORCID 0000-0003-2819-812X
Mary GazeaZentrum für Experimentelle Neurologie, Department of Neurology, Inselspital University Hospital Bern, CH-3010 Bern, Switzerland.ORCID 0000-0003-1468-8419
Thomas C GentZentrum für Experimentelle Neurologie, Department of Neurology, Inselspital University Hospital Bern, CH-3010 Bern, Switzerland.ORCID 0000-0002-0478-5461
Mojtaba BandarabadiZentrum für Experimentelle Neurologie, Department of Neurology, Inselspital University Hospital Bern, CH-3010 Bern, Switzerland.ORCID 0000-0002-4608-1374
Carolina Gutierrez HerreraZentrum für Experimentelle Neurologie, Department of Neurology, Inselspital University Hospital Bern, CH-3010 Bern, Switzerland.
Antoine R AdamantidisZentrum für Experimentelle Neurologie, Department of Neurology, Inselspital University Hospital Bern, CH-3010 Bern, Switzerland; antoine.adamantidis@dbmr.unibe.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During rapid eye movement (REM) sleep, behavioral unresponsiveness contrasts strongly with intense brain-wide neural network dynamics. Yet, the physiological functions of this cellular activation remain unclear. Using in vivo calcium imaging in freely behaving mice, we found that inhibitory neurons in the lateral hypothalamus (LH

Indexed as

AnimalsBrain MappingFeeding BehaviorHypothalamic Area, LateralMaleMiceNerve NetNeural InhibitionNeuronsOptogeneticsSleepSleep, REMVesicular Inhibitory Amino Acid Transport ProteinsVesicular Inhibitory Amino Acid Transport ProteinsViaat protein, mousecalcium imagingfeedinglateral hypothalamusoptogeneticsREM sleep

Identifiers

PMID32732431
PMCPMC7430996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.