Observational studyArchives of disease in childhood. Fetal and neonatal edition2021
Placental transfusion and short-term outcomes among extremely preterm infants.
Observational study in Archives of disease in childhood. Fetal and neonatal edition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00063063 (Generic Database), which is not on this map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Generic Database: A Survey of Morbidity and Mortality in Very Low Birth Weight Infants
Who cites it
7 citing papers in PubMed, 20 citations in OpenAlex.
- Delayed Cord Clamping and Early Neonatal Outcomes in Infants Born Before 30 Weeks of Gestation: A Retrospective Cohort Study.Children (Basel, Switzerland) · 2026Article
- Acceptance and implementation of evidence-based practices in delivery room resuscitation: A qualitative study.SSM. Qualitative research in health · 2025Article
- Oxygen saturation targets in neonatal care: A narrative review.Early human development · 2024Review
- Monitoring and evaluation of hypotension in the extremely preterm.Frontiers in cardiovascular medicine · 2024Review
- Exposure to umbilical cord management approaches and death or neurodevelopmental impairment at 22-26 months' corrected age after extremely preterm birth.Archives of disease in childhood. Fetal and neonatal edition · 2023Article
- Perinatal management: Lessons learned from the neonatal research network.Seminars in perinatology · 2022Article
- Umbilical Cord Milking vs Delayed Cord Clamping and Associations with In-Hospital Outcomes among Extremely Premature Infants.The Journal of pediatrics · 2021Observational
Corrections and comments
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Authors and funding
14 authors at 8 institutions in 1 country.
Funding
Abstract
objectiveTo compare short-term outcomes after placental transfusion (delayed cord clamping (DCC) or umbilical cord milking (UCM)) versus immediate cord clamping among extremely preterm infants.
designRetrospective study.
settingThe PATIENTS: Infants born <29 weeks' gestation in 2016 or 2017 without congenital anomalies who received active treatment after delivery. INTERVENTION/EXPOSURE: DCC or UCM.
main outcome measuresPrimary outcomes: (1) composite of mortality or major morbidity by 36 weeks' postmenstrual age (PMA); (2) mortality by 36 weeks PMA and (3) composite of major morbidities by 36 weeks' PMA. Secondary composite outcomes: (1) any grade intraventricular haemorrhage or mortality by 36 weeks' PMA and (2) hypotension treatment in the first 24 postnatal hours or mortality in the first 12 postnatal hours. Outcomes were assessed using multivariable regression, adjusting for mortality risk factors identified a priori, significant confounders and centre as a random effect.
resultsAmong 3116 infants, 40% were exposed to placental transfusion, which was not associated with the primary composite outcome of mortality or major morbidity by 36 weeks' PMA (adjusted OR (aOR) 1.26, 95% CI 0.95 to 1.66). However, exposure was associated with decreased mortality by 36 weeks' PMA (aOR 0.71, 95% CI 0.55 to 0.92) and decreased hypotension treatment in first 24 postnatal hours (aOR 0.66, 95% CI 0.53 to 0.82).
conclusionIn this extremely preterm infant cohort, exposure to placental transfusion was not associated with the composite outcome of mortality or major morbidity, though there was a reduction in mortality by 36 weeks' PMA. TRIAL REGISTRATION NUMBER: NCT00063063.
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