ArticleThe European respiratory journal2021
Hyperglycaemia in cystic fibrosis adversely affects BK channel function critical for mucus clearance.
Open access · bronzeAbstract read
In one paragraph
Article in The European respiratory journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 19 citations in OpenAlex.
- Potassium Channels of the Airway Epithelium.Acta physiologica (Oxford, England) · 2026Review
- Oral losartan yields subtherapeutic airway exposure compared to nebulized delivery and fails to improve mucociliary clearance in cystic fibrosis.Frontiers in pharmacology · 2026Article
- From Pathophysiology to Treatment: Contemporary Approaches to CFRD in the Pediatric and Adolescent Population.Pediatric diabetes · 2026Review
- Elevated glucose increasesInfection and immunity · 2025Article
- Effects of Elevated Glucose on Bacterial Respiratory Infections in Cystic Fibrosis and Chronic Airway Diseases.International journal of molecular sciences · 2025Review
- Therapeutic strategies to reverse cigarette smoke-induced ion channel and mucociliary dysfunction in COPD airway epithelial cells.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Highly Selective Artificial KJACS Au · 2024Article
- Cystic fibrosis.Nature reviews. Disease primers · 2024Review
- Potentiation of BKCa channels by cystic fibrosis transmembrane conductance regulator correctors VX-445 and VX-121.The Journal of clinical investigation · 2024Article
- The role of potassium ion channels in chronic sinusitis.Frontiers in pharmacology · 2024Review
- E-cigarette aerosols of propylene glycol impair BK channel activity and parameters of mucociliary function.American journal of physiology. Lung cellular and molecular physiology · 2023Article
- Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.International journal of molecular sciences · 2023Article
- Therapeutic applications of curcumin nanomedicine formulations in cystic fibrosis.Progress in biomaterials · 2022Review
- The CFTR Amplifier Nesolicaftor Rescues TGF-β1 Inhibition of Modulator-Corrected F508del CFTR Function.International journal of molecular sciences · 2022Article
- Losartan ameliorates TGF-β1-induced CFTR dysfunction and improves correction by cystic fibrosis modulator therapies.The Journal of clinical investigation · 2022Article
- A medium composition containing normal resting glucose that supports differentiation of primary human airway cells.Scientific reports · 2022Article
- Vegetable glycerin e-cigarette aerosols cause airway inflammation and ion channel dysfunction.Frontiers in pharmacology · 2022Article
- Revisiting the Large-Conductance Calcium-Activated Potassium (BKCa) Channels in the Pulmonary Circulation.Biomolecules · 2021Review
- Assessment of efficacy and tolerability of elexacaftor-tezacaftor-ivacaftor in an observational cohort study of "aged" people with cystic fibrosis.Therapeutic advances in respiratory diseaseObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Charles D BengtsonDept of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Michael D KimDept of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Abeer AnabtawiDept of Internal Medicine, Division of Endocrinology, Metabolism, and Genetics, University of Kansas Medical Center, Kansas City, KS, USA.
Jianghua HeDept of Biostatistics and Data Science, University of Kansas Medical Center, Kansas City, KS, USA.
John S DennisDept of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Sara MillerDept of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Makoto YoshidaDept of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Nathalie BaumlinDept of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Matthias SalatheDept of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, USA msalathe@kumc.edu.ORCID 0000-0001-9092-4861
University of Kansas Medical Center · US
Funding
RADx-UP: Improving the Response of Local Urban and Rural Communities to Disparities in Covid-19 TestingUL1TR002366 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Mario Castro, JAMES STEVEN LEEDER · 2017 to 2026
$44.3MNRSA Training CoreTL1TR002368 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Jennifer Lynn Goldman, NICOLE L NOLLEN · 2017 to 2026
$4.0MAnti-inflammatory therapy to augment CFTR rescue in CF patientsR01HL133240 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SALATHE, MATTHIAS A · 2017 to 2020
$2.7MMechanisms of mucociliary dysfunction in cystic fibrosis related diabetesR01HL157942 · NHLBI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI KIM, MICHAEL D, SALATHE, MATTHIAS A · 2021 to 2024
$2.7MNCATS NIH HHS TL1 TR002368NCATS NIH HHS UL1 TR002366NHLBI NIH HHS R01 HL133240NHLBI NIH HHS R01 HL157942
Abstract
Large-conductance, Ca
Indexed as
Cystic FibrosisHyperglycemiaBlood GlucoseBlood Glucose Self-MonitoringCystic Fibrosis Transmembrane Conductance RegulatorHumansLarge-Conductance Calcium-Activated Potassium ChannelsMucusReceptor for Advanced Glycation End ProductsRespiratory MucosaBlood GlucoseCystic Fibrosis Transmembrane Conductance RegulatorLarge-Conductance Calcium-Activated Potassium ChannelsReceptor for Advanced Glycation End Products
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.