Evidence map›Paper›PMID 32732307›Full record

ArticleG3 (Bethesda, Md.)2020

Low Base-Substitution Mutation Rate but High Rate of Slippage Mutations in the Sequence Repeat-Rich Genome of

Sibel Kucukyildirim, Megan Behringer, Way Sung, Debra A Brock, Thomas G Doak, Hatice Mergen, David C Queller, Joan E Strassmann, Michael Lynch

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Sibel KucukyildirimDepartment of Biology, Indiana University, Bloomington, IN 47405 sibelkucukyildirim@gmail.com.ORCID 0000-0003-2241-3060
Megan BehringerDepartment of Biology, Indiana University, Bloomington, IN 47405.ORCID 0000-0001-7036-6014
Way SungDepartment of Bioinformatics and Genomics, University of North Carolina, Charlotte, NC, 28223.ORCID 0000-0002-8336-8913
Debra A BrockDepartment of Biology, Washington University, St. Louis, MO 63130.ORCID 0000-0002-4349-5854
Thomas G DoakDepartment of Biology, Indiana University, Bloomington, IN 47405.ORCID 0000-0001-5487-553X
Hatice MergenDepartment of Biology, Hacettepe University, Ankara 06800 TURKEY.ORCID 0000-0002-7980-8197
David C QuellerDepartment of Biology, Washington University, St. Louis, MO 63130.ORCID 0000-0002-5464-1984
Joan E StrassmannDepartment of Biology, Washington University, St. Louis, MO 63130.ORCID 0000-0003-0638-8440
Michael LynchBiodesign Center for Mechanisms of Evolution, Arizona State University, Tempe, AZ.
Washington University in St. Louis · USHacettepe University · TRIndiana University Bloomington · USArizona State University · USUniversity of North Carolina at Charlotte · US

Funding

Causes and Population-genetic Consequences of Molecular VariationR35GM122566 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Michael R LYNCH · 2017 to 2026
$7.7M
The Rate and Molecular Spectrum of Spontaneous MutationsR01GM036827 · NIGMS · UNIVERSITY OF OREGON · PI LYNCH, MICHAEL R · 1988 to 2016
$5.7M
Genetic and Environmental Determinants of Population Structure During Escherichia coli Experimental Evolution.F32GM123703 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI BEHRINGER, MEGAN GRACE · 2017 to 2018
$118k
NIGMS NIH HHS F32 GM123703NIGMS NIH HHS R01 GM036827NIGMS NIH HHS R35 GM122566
6 · The paper itself

Abstract

We describe the rate and spectrum of spontaneous mutations for the social amoeba

Indexed as

DictyosteliumEvolution, MolecularGenomeMutationMutation RateDictyostelium discoideumdrift-barrier hypothesisinsertion-deletion biasmutationsimple sequence repeats

Identifiers

PMID32732307
PMCPMC7466956
OpenAlexW3046815644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.