Evidence map›Paper›PMID 32732272›Full record

ArticleAJNR. American journal of neuroradiology2020

Pretreatment DWI with Histogram Analysis of the ADC in Predicting the Outcome of Advanced Oropharyngeal Cancer with Known Human Papillomavirus Status Treated with Chemoradiation.

M Ravanelli, A Grammatica, M Maddalo, M Ramanzin, G M Agazzi, E Tononcelli, S Battocchio, P Bossi, M Vezzoli, R Maroldi and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 5 countries.

M RavanelliFrom the Departments of Radiology (M. Ravanelli, M. Ramanzin, G.M.A., E.T., R.M., D.F.).ORCID 0000-0002-4841-2771
A GrammaticaOtorhinolaryngology (A.G.).ORCID 0000-0001-7084-8603
M MaddaloRadiation Oncology (M.M.).ORCID 0000-0002-1410-4009
M RamanzinFrom the Departments of Radiology (M. Ravanelli, M. Ramanzin, G.M.A., E.T., R.M., D.F.) marco.ramanzin91@gmail.com.ORCID 0000-0003-1497-5952
G M AgazziFrom the Departments of Radiology (M. Ravanelli, M. Ramanzin, G.M.A., E.T., R.M., D.F.).ORCID 0000-0002-7347-3293
E TononcelliFrom the Departments of Radiology (M. Ravanelli, M. Ramanzin, G.M.A., E.T., R.M., D.F.).ORCID 0000-0002-4423-7056
S BattocchioPathological Anatomy (S.B.).ORCID 0000-0002-4868-0397
P BossiMedical Oncology (P.B.).ORCID 0000-0003-0135-0224
M VezzoliMolecular and Translational Medicine (M.V.), University of Brescia, Brescia, Italy.ORCID 0000-0002-0424-4235
R MaroldiFrom the Departments of Radiology (M. Ravanelli, M. Ramanzin, G.M.A., E.T., R.M., D.F.).ORCID 0000-0001-5664-353X
D FarinaFrom the Departments of Radiology (M. Ravanelli, M. Ramanzin, G.M.A., E.T., R.M., D.F.).ORCID 0000-0003-4075-0001
RSPC MT · BYIstituto Ramazzini · ITPalmetto Hematology Oncology · USPathological Society · GBPCR Oncology · USScientific Research Clinical Institute. L.I. Sverzhevsky · RUUniversity of Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe incidence of oropharyngeal squamous cell carcinoma (OPSCC) has increased in the period from the 1970s to 2004, due to increase of infection with human papilloma virus (HPV). This study aimed to examine the role of histogram analysis of the ADC in treatment response and survival prediction of patients with oropharyngeal squamous cell carcinoma and known human papillomavirus status. MATERIALS AND

methodsThis was a retrospective single-center study. Following inclusion and exclusion criteria, data for 59 patients affected by T2-T4 (according to the 8th edition of the

resultsAt univariable analysis, both human papillomavirus status and mean ADC were associated with progression-free survival (hazard ratio = 0.267,

conclusionsADC and human papillomavirus status are related to progression-free survival in patients treated with chemoradiation for advanced oropharyngeal squamous cell carcinoma; however, this association seems to result from the strong association between ADC and human papillomavirus status.

Indexed as

AdultAgedChemoradiotherapyDiffusion Magnetic Resonance ImagingFemaleHead and Neck NeoplasmsHumansImage Interpretation, Computer-AssistedMaleMiddle AgedPapillomavirus InfectionsProgression-Free SurvivalRetrospective StudiesSquamous Cell Carcinoma of Head and Neck

Identifiers

PMID32732272
PMCPMC7658864
OpenAlexW3046572970

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.