SynthesisAJNR. American journal of neuroradiology2020
Incidence and Risk Factors of In-Stent Restenosis for Symptomatic Intracranial Atherosclerotic Stenosis: A Systematic Review and Meta-Analysis.
Synthesis in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Drug-eluting stents versus bare-metal stents for intracranial atherosclerotic stenosis: a systematic review and meta-analysis.BMJ open · 2024Pooled it
- Efficacy and safety of drug-eluting stents versus bare-metal stents in symptomatic intracranial and vertebral artery stenosis: a meta-analysis.Frontiers in neurology · 2024Pooled it
- Drug-coated Balloons in the Neurovascular Setting: A Comprehensive, Systematic Review of Current Use and Indications.Reviews in cardiovascular medicine · 2022Pooled it
- Comparison of Drug-Eluting Stent With Bare-Metal Stent in Patients With Symptomatic High-grade Intracranial Atherosclerotic Stenosis: A Randomized Clinical Trial.JAMA neurology · 2022Trial
- Predictive Value of Baseline High-Resolution MRI Features for In-Stent Restenosis in Symptomatic Nonacute Intracranial Atherosclerotic Occlusion.Cardiovascular and interventional radiology · 2026Article
- Seeing Intracranial in-Stent Restenosis Before it Happens: What Baseline Vessel Wall Imaging Can-and Can't-Tell Us Yet.Cardiovascular and interventional radiology · 2026Article
- Dramatically changing intracranial arteriopathy due to antiphospholipid syndrome: A case report.Radiology case reports · 2026Article
- Short-term outcomes of intracranial angioplasty with the Neuroform EZ stent in patients with hypoperfusion-related symptomatic intracranial atherosclerotic stenosis.BMC neurology · 2026Article
- Effect of Angiographic Hemodynamic Parameters and Vascular Tortuosity on In-Stent Restenosis in Intracranial Atherosclerosis.Clinical neuroradiology · 2026Article
- Pre-procedural C-reactive protein levels and carotid or intracranial artery restenosis: A systematic review and meta-analysis.Atherosclerosis plus · 2026Article
- Beyond mechanical revascularization: thrombo-inflammatory mechanisms and vascular bed-specific design of intracranial stents.Frontiers in molecular biosciences · 2026Review
- Endovascular Therapy for Intracranial Atherosclerotic Stenosis: Evidence and Controversies.Journal of neuroendovascular therapy · 2026Review
- Exploratory analysis of morphology-hemodynamics-perfusion relationships after intracranial stenting in severe intracranial atherosclerotic stenosis.Frontiers in neurology · 2026Article
- Photon-Counting CT-Angiography to Assess Intracranial Stents and Flow Diverters in Comparison to Digital Subtraction Angiography.Clinical neuroradiology · 2025Article
- Higher Time to Peak after Stent Implantation in Symptomatic High-Grade Intracranial Atherosclerotic Stenosis is Related to In-Stent Restenosis.Translational stroke research · 2025Article
- Development and validation of a nomogram for in-stent restenosis within 2 years in patients after iliac or femoral artery stent placement.BMC surgery · 2025Article
- Net meta-analysis: comparison of bare metal stent, drug-coated balloon and drug-eluting stent in the treatment of cerebral arterial stenosis.Frontiers in neurology · 2025Review
- Roles of Nontraditional Lipid Parameters for Predicting Restenosis in Patients with Intracranial Atherosclerotic Stenosis After Endovascular Treatment.Clinical neuroradiology · 2024Article
- Article
- Telomere length as a biomarker for cerebrovascular diseases: current evidence.Molecular biology reports · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn-stent restenosis affects long-term outcome in patients with intracranial atherosclerotic stenosis. PURPOSE: The aim of this meta-analysis was to evaluate the incidence and risk factors of in-stent restenosis. DATA SOURCES: All literature that reported in-stent restenosis was searched on PubMed, Ovid EMBASE and Ovid MEDLINE data bases. STUDY SELECTION: Original articles about stents for symptomatic intracranial atherosclerotic stenosis were selected. DATA ANALYSIS: Meta-analysis was conducted to derive the pooled in-stent restenosis using a random-effects model. Meta-regression was performed to explore the risk factors predisposing to in-stent restenosis. DATA SYNTHESIS: In total, 51 studies with 5043 patients were included. The pooled incidence rate of in-stent restenosis was 14.8% (95% CI, 11.9%-17.9%). Among the lesions with in-stent restenosis, 28.8% of them led to (95% CI, 22.0%-36.0%) related neurologic symptoms. The series in the United States had a higher in-stent restenosis rate (27.0%; 95% CI, 20.6%-33.9%) compared with those from Asia (13.6%; 95% CI, 10.3%-17.2%) and other regions as a whole (7.6%; 95% CI, 1.1%-18.1%) ( LIMITATIONS: The heterogeneity of most outcomes was high.
conclusionsOur study showed promising results of in-stent restenosis for symptomatic atherosclerotic stenosis. Studies are needed to further expatiate on the mechanisms by which younger patient age, vertebrobasilar junction location, and low residual stenosis could increase in-stent restenosis and symptomatic in-stent restenosis, respectively.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.