Evidence map›Paper›PMID 32732018›Full record

SynthesisJournal of the National Medical Association2021

Uncovering Outcome Disparities of β

Rebecca N Jerome, Jill M Pulley, Nila A Sathe, Shanthi Krishnaswami, Alyssa B Dickerson, Katherine J Worley, Maria F Lima, Consuelo H Wilkins

Open access · greenAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of the National Medical Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Place of death from asthma differs by age, race, and ethnicity.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2023
    Article
  2. Review
  3. Pharmacogenetics of Bronchodilator Response: Future Directions.Current allergy and asthma reports · 2021
    Review
  4. Genetic Determinants of Poor Response to Treatment in Severe Asthma.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rebecca N JeromeVanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: rebecca.jerome@vumc.org.
Jill M PulleyVanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Nila A SatheVanderbilt Evidence-Based Practice Center, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Health Policy, Vanderbilt University Medical Center, Nashville, TN, USA.
Shanthi KrishnaswamiVanderbilt Evidence-Based Practice Center, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN, USA.
Alyssa B DickersonVanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Katherine J WorleyVanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Evidence-Based Practice Center, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN, USA.
Maria F LimaSchool of Graduate Studies and Research, Meharry Medical College, Nashville, TN, USA.
Consuelo H WilkinsDepartment of Medicine, Vanderbilt University Medical Center and Department of Internal Medicine, Meharry Medical College, Nashville, TN, USA.
Vanderbilt University Medical Center · USMeharry Medical College · US

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Training and Mentoring CoreU54MD010722 · NIMHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WILKINS, CONSUELO HOPKINS · 2016 to 2020
$11.9M
NCATS NIH HHS UL1 TR002243NIMHD NIH HHS U54 MD010722
6 · The paper itself

Abstract

purposeOutcome differences driven by variation in Blacks' biologic response to treatment may contribute to persistent racial disparities in asthma morbidity and mortality. This review assessed systematic variation in β

methodsWe conducted a systematic review of studies reporting differential response to β

resultsOf 3158 papers, 20 compared safety or efficacy of β

conclusionsEvidence suggests the potential for differences in β

Indexed as

AsthmaBlack or African AmericanAdministration, InhalationAdrenergic AgonistsDrug Therapy, CombinationHumansAdrenergic AgonistsAsthmaBeta-2 adrenergic agonistsRacial disparitiesSafetyTreatment response

Identifiers

PMID32732018
PMCPMC7855752
OpenAlexW3045610105

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.