Evidence map›Paper›PMID 32731898›Full record

ArticleBMC pediatrics2020

The correlation between vitamin a status and refractory Mycoplasma Pneumoniae pneumonia (RMPP) incidence in children.

Yuanyuan Li, Ziyao Guo, Guangli Zhang, Xiaoyin Tian, Qinyuan Li, Dapeng Chen, Zhengxiu Luo

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Independent risk factors for refractory mycoplasma pneumoniae pneumonia in children: a multivariate analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
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  4. Early prediction of plastic bronchitis in pediatric patients withFrontiers in cellular and infection microbiology · 2026
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  5. Clinical characteristics ofFrontiers in pediatrics · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. A comprehensive review ofFrontiers in medicine · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yuanyuan LiChongqing Key Laboratory of Pediatrics, China International Science and Technology Cooperation base of Child Development and Critical Disorders, Chongqing, 400014, China.
Ziyao GuoChongqing Key Laboratory of Pediatrics, China International Science and Technology Cooperation base of Child Development and Critical Disorders, Chongqing, 400014, China.
Guangli ZhangDepartment of Respiratory Medicine Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 400014, China.
Xiaoyin TianDepartment of Respiratory Medicine Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 400014, China.
Qinyuan LiChongqing Key Laboratory of Pediatrics, China International Science and Technology Cooperation base of Child Development and Critical Disorders, Chongqing, 400014, China.
Dapeng ChenDepartment of Clinical Laboratory center, Children's Hospital of Chongqing Medical University, Chongqing, 400014, China.
Zhengxiu LuoDepartment of Respiratory Medicine Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 400014, China. luozhengxiu816@hospital.cqmu.edu.cn.ORCID 0000-0003-3029-9624
Children's Hospital of Chongqing Medical University · CNChina International Science and Technology Cooperation · CN

Funding

National Key Clinical Specialty Discipline Construction Program of China 2011-873
6 · The paper itself

Abstract

backgroundVitamin A plays a pivotal role in respiratory infection, accurate estimation of vitamin A status was recommended in planning and implementing interventions. As infections affect serum vitamin A productions, the real status need to be adjusted by acute phase protein (APP). Mycoplasma pneumoniae is an important cause of respiratory infection in children, the association between vitamin A concentrations and refractory Mycoplasma pneumoniae pneumonia (RMPP) remains unclear.

methods181 MPP patients were enrolled in this retrospective study, adjusted vitamin A concentrations and other parameters were compared between RMPP and general-MPP (GMPP) patients. Multivariate logistic regression test was performed to evaluate the association between vitamin A levels and RMPP incidence, linear correlation tests were applied to evaluate correlation between vitamin A concentrations and fever duration, length of stay (LOS).

resultsVitamin A concentrations in RMPP group were significantly lower than those in GMPP patients (P < 0.05), vitamin A (OR = 0.795, 95% C. I 0.669-0.946) and CRP (OR = 1.050, 95% C. I 1.014-1.087) were independently associated with RMPP incidence. Linear correlation tests found vitamin A concentrations were negatively correlated with fever duration and LOS (P < 0.001).

conclusionsSerum vitamin A concentrations were independently associated with RMPP incidence, which may correlate with reduced incidence of RMPP.

Indexed as

Mycoplasma pneumoniaePneumonia, MycoplasmaChildC-Reactive ProteinHumansIncidenceRetrospective StudiesVitamin AC-Reactive ProteinVitamin AMycoplasma Pneumoniae pneumonia (MPP)Retinol-binding protein (RBP)Vitamin a

Identifiers

PMID32731898
PMCPMC7392651
OpenAlexW3046727995

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.