Evidence map›Paper›PMID 32731888›Full record

ArticleBMC complementary medicine and therapies2020

Prescription patterns and factors influencing the use of Chinese herbal medicine among pregnant women in Taiwan: a population-based retrospective study.

Shu-Hui Wen, Wei-Chuan Chang, Hsuan-Shu Shen, Hsien-Chang Wu

Open access · goldAbstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shu-Hui WenDepartment of Public Health, College of Medicine, Tzu Chi University, Hualien, Taiwan.
Wei-Chuan ChangDepartment of Medical Research, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Hsuan-Shu ShenDepartment of Chinese Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Hsien-Chang WuSchool of Post-baccalaureate Chinese Medicine, Tzu Chi University, Hualien, Taiwan. dr30032@gmail.com.ORCID http://orcid.org/0000-0002-2374-0955
Tzu Chi University · TWBuddhist Tzu Chi General Hospital · TW

Funding

Taipei Tzu Chi Hospital TCRD-TPE-106-22
6 · The paper itself

Abstract

backgroundThe use of Chinese herbal medicine (CHM) has been widely promoted as a natural and safe way to treat illness during pregnancy. However, prescription patterns and factors influencing its use are largely unknown. Therefore, we conducted a population-based study to address these questions.

methodsPregnant women aged 18-50 years were selected from Taiwan's National Health Insurance Research Database between 2001 to 2011. CHM prescriptions and diagnostic records were collected. Demographic data and pre-existing diseases were compared between CHM users and non-users. A multivariate logistic regression analysis was performed to identify possible factors influencing the use of CHM during pregnancy.

resultsA total of 81,873 eligible prescription records were identified, and 16,553 pregnant women were prescribed CHM during pregnancy, yielding a CHM prescription rate of 20.2%. The three most frequently used herbs were Scutellariae Radix (Huang Qin) (4.4%), Eucommiae cortex (Du Zhong) (2.5%), and Atractylodes Rhizome (Bai Zhu) (2.4%). The most frequently used herbal formulae were Dang-Guei-Shao-Yao-San (4.1%), Jia-Wei-Xiao-Yao-San (3.5%), and Xiang-Sha-Liu-Jun-Zi-Tang (2.6%). Multivariate logistic regression revealed that subjects with an older age, a university education, a pre-pregnancy history of CHM use, asthma, chronic renal disease, and cardiac valvular disease and living in a residential area other than northern Taiwan had an increase in adjusted odds ratio for CHM use during pregnancy.

conclusionsIn this population-based study, we found that demographic factors and pre-existing diseases were associated with the use of CHM among pregnant women. It is worth noting that Leonuri Herba (Yi Mu Cao) and Shao-Fu-Zhu-Yu-Tang should be used with caution in the first trimester. Further research is needed to explore the safety and effectiveness of the use of CHM in pregnant women.

Indexed as

AdolescentAdultDrugs, Chinese HerbalFemaleHumansMedicine, Chinese TraditionalMiddle AgedPractice Patterns, Physicians'PregnancyPregnancy ComplicationsRetrospective StudiesTaiwanYoung AdultDrugs, Chinese HerbalAlternative medicineChinese herbal medicinePerinatalPeripartumPregnant womenTraditional Chinese medicine

Identifiers

PMID32731888
PMCPMC7391530
OpenAlexW3045798084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.