Evidence map›Paper›PMID 32731872›Full record

SynthesisWorld journal of surgical oncology2020

Clinicopathological and prognostic significance of platelet-lymphocyte ratio (PLR) in gastric cancer: an updated meta-analysis.

Xunlei Zhang, Wenjing Zhao, Yang Yu, Xue Qi, Li Song, Chenfei Zhang, Guoxing Li, Lei Yang

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in World journal of surgical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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  11. Investigating the predictive role of inflammatory indices in cancer metastasis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xunlei ZhangDepartment of Oncology, Tumor Hospital Affiliated to Nantong University, Nantong, 226300, Jiangsu, China.
Wenjing ZhaoCancer Research Center Nantong, Tumor Hospital Affiliated to Nantong University, Nantong, 226300, Jiangsu, China.
Yang YuDepartment of Oncology, Tumor Hospital Affiliated to Nantong University, Nantong, 226300, Jiangsu, China.
Xue QiDepartment of Oncology, Nantong Liangchun Hospital of Traditional Chinese Medicine, Nantong, 226300, Jiangsu, China.
Li SongDepartment of Oncology, Tumor Hospital Affiliated to Nantong University, Nantong, 226300, Jiangsu, China.
Chenfei ZhangDepartment of Oncology, Tumor Hospital Affiliated to Nantong University, Nantong, 226300, Jiangsu, China.
Guoxing LiDepartment of General Surgery, Tumor Hospital Affiliated to Nantong University, Nantong, 226300, Jiangsu, China. liguoxing1986@126.com.
Lei YangDepartment of Oncology, Tumor Hospital Affiliated to Nantong University, Nantong, 226300, Jiangsu, China. leiyang.53@163.com.ORCID http://orcid.org/0000-0002-3724-3407

Funding

Project for Medical Key Youth Talent of Nantong Youth 005Youth Research Fund Project of the Health and Family Planning Commission of Nantong WQ2015052
6 · The paper itself

Abstract

backgroundPre-treatment PLR (platelet-lymphocyte ratio) was reported to be associated with the prognosis in gastric cancer (GC), but the results remain inconclusive. This meta-analysis aimed to investigate the prognostic potential of the pre-treatment PLR in gastric cancer.

methodsWe performed a systematic literature search in PubMed, Embase, and the Cochrane Library to identify eligible publications. The hazard ratio (HR)/odds ratio (OR) and its 95% confidence (CI) of survival outcomes and clinicopathological parameters were calculated.

resultsA total of 49 studies (51 cohorts), collecting data from 28,929 GC patients, were included in the final analysis. The pooled results demonstrated that the elevated pre-treatment PLR was significantly associated with poor overall survival (OS) (HR 1.37, 95% CI 1.26-1.49, p < 0.001; I

conclusionsAn elevated pre-treatment PLR was a prognostic factor for poor OS and DFS and associated with poor clinicopathological parameters in GC patients.

Indexed as

Stomach NeoplasmsBlood PlateletsHumansLymphocyte CountLymphocytesPlatelet CountPrognosisGastric cancerLymphocyteMeta-analysisPlateletPLR

Identifiers

PMID32731872
PMCPMC7391520

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.