ArticleThe American journal of psychiatry2021
Reward Processing in Children With Disruptive Behavior Disorders and Callous-Unemotional Traits in the ABCD Study.
Article in The American journal of psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Aberrant Resting-State Functional Connectivity Associated With Callous-Unemotional Traits From Late Childhood Through Late Adolescence.Biological psychiatry global open science · 2026Article
- Correction of Reward Processing Deficits in Youth with Disruptive Behavior and Trauma Exposure: A Pilot Study of Neural Responses to Fluoxetine.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026Article
- Resting-state brain function and its modulation by intranasal oxytocin in antisocial personality disorder with and without psychopathy.Scientific reports · 2026Article
- Blunted reward-related striatal activity and behavioral disinhibition as a pathway to adolescent cannabis and e-cigarette use.Frontiers in adolescent medicine · 2026Article
- Article
- Reward Motives are Differentially Related to Depression, Anxiety, and ADHD Symptoms in Middle Childhood.International journal of behavioral development · 2025Article
- Neural reward processing among children with conduct disorder and mild traumatic brain injury in the ABCD study.Psychological medicine · 2025Article
- The impact of anger on intertemporal decision-making in individuals with internet addiction: an fNIRS study.European archives of psychiatry and clinical neuroscience · 2025Article
- Alterations in Region-Specific Gray Matter Volume Underlying Callous Unemotional Traits in Adolescents.Brain and behavior · 2025Article
- Independent Impacts of Maltreatment and Amygdala Volume on Worsening Callous-Unemotional Traits in High-Risk Youths.Research on child and adolescent psychopathology · 2025Article
- Electrophysiological indices of reward anticipation as ADHD risk and prognostic biomarkers.European child & adolescent psychiatry · 2025Article
- Investigating cross-sectional and longitudinal relationships between brain structure and distinct dimensions of externalizing psychopathology in the ABCD sample.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Neural mechanisms of reward processing in preadolescent irritability: Insights from the ABCD study.Journal of affective disorders · 2025Article
- Reinforcement learning processes as forecasters of depression remission.Journal of affective disorders · 2025Article
- Sex-Specific Vulnerability to Externalizing Problems: Sensitivity to Early Stress and Nucleus Accumbens Activation Over Adolescence.Biological psychiatry · 2025Article
- The longitudinal association between reward processing and symptoms of video game addiction in the Adolescent Brain Cognitive Development Study.Journal of behavioral addictions · 2024Article
- Prospective associations between early adolescent reward functioning and later dimensions of psychopathology.Journal of psychopathology and clinical science · 2024Article
- Involving Parents in Cognitive Behavioral Therapy for Children and Adolescents with Conduct Problems: Goals, Outcome Expectations, and Normative Beliefs About Aggression are Targeted in Sessions with Parents and Their Child.Clinical child and family psychology review · 2024Review
- Identification of a Composite Latent Dimension of Reward and Impulsivity Across Clinical, Behavioral, and Neurobiological Domains Among Youth.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- Functional Connectivity of the Nucleus Accumbens across Variants of Callous-Unemotional Traits: A Resting-State fMRI Study in Children and Adolescents.Research on child and adolescent psychopathology · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
objectiveDisrupted reward processing is implicated in the etiology of disruptive behavior disorders (DBDs) and callous-unemotional traits. However, neuroimaging investigations of reward processing underlying these phenotypes remain sparse. The authors examined neural sensitivity in response to reward anticipation and receipt among youths with DBDs, with and without callous-unemotional traits.
methodsData were obtained from the Adolescent Brain and Cognitive Development Study (mean age=9.51 years [SD=0.50]; 49% female). Reward-related activation during the monetary incentive delay task was examined across 16 brain regions, including the amygdala, anterior cingulate cortex (ACC), nucleus accumbens (NAcc), and orbitofrontal cortex (OFC). Latent variable modeling was used to examine network-level coactivation. The following diagnostic groups were compared: typically developing youths (N=693) and youths with DBDs (N=995), subdivided into those with callous-unemotional traits (DBD+CU, N=198) and without callous-unemotional traits (DBD only, N=276).
resultsDuring reward anticipation, youths in the overall DBD group (with and without callous-unemotional traits) showed decreased dorsal ACC activation compared with typically developing youths. The DBD-only group exhibited reduced ventral and dorsal striatal activity compared with the DBD+CU and typically developing groups. During reward receipt, youths with DBDs showed increased cortical (e.g., OFC) and subcortical (e.g., NAcc) regional activation compared with typically developing youths. The DBD+CU group demonstrated greater activation in several regions compared with those in the typically developing (e.g., amygdala) and DBD-only (e.g., dorsal ACC) groups. At the network level, the DBD-only group showed reduced anticipatory reward activation compared with the typically developing and DBD+CU groups, whereas youths in the DBD+CU group showed increased activation during reward receipt compared with those in the typically developing group.
conclusionsThese findings advance our understanding of unique neuroetiologic pathways to DBDs and callous-unemotional traits.
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