Evidence map›Paper›PMID 32731529›Full record

ArticleMolecules (Basel, Switzerland)2020

Oral Bioavailability Evaluation of Celastrol-Encapsulated Silk Fibroin Nanoparticles Using an Optimized LC-MS/MS Method.

Shuyu Zhan, Amy Paik, Felicia Onyeabor, Baoyue Ding, Sunil Prabhu, Jeffrey Wang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Localized NF-κB Inhibition Reduces Lipid Nanoparticle-Associated Inflammation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Shuyu ZhanDepartment of Pharmacy, College of Medicine, Jiaxing University, Jiaxing 314001, China.ORCID 0000-0002-5973-6579
Amy PaikDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA.
Felicia OnyeaborDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA.
Baoyue DingDepartment of Pharmacy, College of Medicine, Jiaxing University, Jiaxing 314001, China.
Sunil PrabhuDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA.
Jeffrey WangDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA.ORCID 0000-0002-6918-2821
Western University of Health Sciences · USJiaxing University · CN

Funding

Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China LY18H280011; 81503338
6 · The paper itself

Abstract

Celastrol (CL), a compound isolated from

Indexed as

Drug CarriersFibroinsNanoparticlesTriterpenesAdministration, OralAnimalsBiological AvailabilityCapsulesChromatography, LiquidDrug Evaluation, PreclinicalMaleMass SpectrometryPentacyclic TriterpenesRatsRats, Sprague-DawleyCapsulescelastrolDrug CarriersFibroinsPentacyclic TriterpenesTriterpenesbioavailabilitycelastrolLC-MS/MSpharmacokineticssilk fibroin nanoparticles

Identifiers

PMID32731529
PMCPMC7435660
OpenAlexW3045874314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.