Evidence map›Paper›PMID 32731492›Full record

ArticleJournal of clinical medicine2020

Association between Hyperacusis and Tinnitus.

Christopher R Cederroth, Alessandra Lugo, Niklas K Edvall, Andra Lazar, Jose-Antonio Lopez-Escamez, Jan Bulla, Inger Uhlen, Derek J Hoare, David M Baguley, Barbara Canlon and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 5 pooled it
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 5 syntheses or guidelines pooled it, 87 citations in OpenAlex.

  1. A Systematic Review on the Genetic Contribution to Tinnitus.Journal of the Association for Research in Otolaryngology : JARO · 2024
    Pooled it
  2. Pooled it
  3. Screening for Circulating Inflammatory Proteins Does Not Reveal Plasma Biomarkers of Constant Tinnitus.Journal of the Association for Research in Otolaryngology : JARO · 2023
    Pooled it
  4. Low Evidence for Tinnitus Risk Factors: A Systematic Review and Meta-analysis.Journal of the Association for Research in Otolaryngology : JARO · 2023
    Pooled it
  5. Pooled it
  6. Trial
  7. Tinnitus: A Dimensionally Segregated, yet Perceptually Integrated Heterogeneous Disorder.Journal of the Association for Research in Otolaryngology : JARO · 2024
    Trial
  8. Tinnitus.Nature reviews. Disease primers · 2026
    Review
  9. Article
  10. Article
  11. Exploring the Link Between Tinnitus and Loudness Intolerance.International archives of otorhinolaryngology · 2026
    Article
  12. Article
  13. Observational
  14. Article
  15. Investigation of Hyperacusis in Patients with Tinnitus.Iranian journal of otorhinolaryngology · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Inhibition of Cortical Evoked Responses to Sound Pulses by Preceding Silent Gaps.Journal of the Association for Research in Otolaryngology : JARO · 2025
    Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 6 countries.

Christopher R CederrothLaboratory of Experimental Audiology, Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0001-7267-5136
Alessandra LugoDepartment of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
Niklas K EdvallLaboratory of Experimental Audiology, Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden.
Andra LazarHörsel och balansmottagningen, Karolinska Universitetssjukhuset, 171 76 Stockholm, Sweden.
Jose-Antonio Lopez-EscamezOtology & Neurotology Group, Department of Genomic Medicine, Pfizer-Universidad de Granada-Junta de Andalucía Centro de Genómica e Investigación Oncológica (GENYO), PTS, Avenida de la Ilustración 114, 18016 Granada, Spain.ORCID 0000-0002-8583-1430
Jan BullaDepartment of Mathematics, University of Bergen, 5020 Bergen, Norway.ORCID 0000-0003-3308-0652
Inger UhlenHörsel och balansmottagningen, Karolinska Universitetssjukhuset, 171 76 Stockholm, Sweden.
Derek J HoareNational Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Ropewalk House, Nottingham NG1 5DU, UK.ORCID 0000-0002-8768-1392
David M BaguleyNational Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Ropewalk House, Nottingham NG1 5DU, UK.
Barbara CanlonLaboratory of Experimental Audiology, Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden.
Silvano GallusDepartment of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
Nottingham University Hospitals NHS Trust · GBKarolinska Institutet · SEKarolinska University Hospital · SEMario Negri Institute for Pharmacological Research · ITInstituto de Investigación Biosanitaria de Granada · ESUniversity of Bergen · NO

Funding

European Union's Horizon 2020 Research and Innovation Programme 848261European Union's Horizon 2020 Research and Innovation Programme under the Marie Skłodowska-Curie grant agreement 72204655GENDER-NET Co-Plus Fund GNP-182
6 · The paper itself

Abstract

Many individuals with tinnitus report experiencing hyperacusis (enhanced sensitivity to sounds). However, estimates of the association between hyperacusis and tinnitus is lacking. Here, we investigate this relationship in a Swedish study. A total of 3645 participants (1984 with tinnitus and 1661 without tinnitus) were enrolled via LifeGene, a study from the general Swedish population, aged 18-90 years, and provided information on socio-demographic characteristics, as well as presence of hyperacusis and its severity. Tinnitus presence and severity were self-reported or assessed using the Tinnitus Handicap Inventory (THI). Phenotypes of tinnitus with (

Indexed as

headachehearing losshyperacusismigrainesomatosensorysubtypetinnitusTMJ

Identifiers

PMID32731492
PMCPMC7465629
OpenAlexW3045802470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.