Evidence map›Paper›PMID 32731464›Full record

ReviewAntibiotics (Basel, Switzerland)2020

From Ocean to Medicine: Pharmaceutical Applications of Metabolites from Marine Bacteria.

José Diogo Santos, Inês Vitorino, Fernando Reyes, Francisca Vicente, Olga Maria Lage

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Unveiling the bioactive potential of Actinomycetota from the Tagus River estuary.International microbiology : the official journal of the Spanish Society for Microbiology · 2024
    Article
  10. Article
  11. Review
  12. Saturated Iso-Type Fatty Acids from the Marine BacteriumPharmaceuticals (Basel, Switzerland) · 2024
    Article
  13. In Silico Screening of Bacteriocin Gene Clusters within a Set of MarineInternational journal of molecular sciences · 2024
    Article
  14. Article
  15. Exploring the seas for cancer cures: the promise of marine-derived bioactive peptide.International journal of biochemistry and molecular biology · 2024
    Review
  16. Four NovelViruses · 2023
    Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

José Diogo SantosDepartment of Biology, Faculty of Sciences, University of Porto, Rua do Campo Alegre s/n, 4169-007 Porto, Portugal.ORCID 0000-0002-9693-4857
Inês VitorinoDepartment of Biology, Faculty of Sciences, University of Porto, Rua do Campo Alegre s/n, 4169-007 Porto, Portugal.
Fernando ReyesFundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avenida del Conocimiento, 34 Parque Tecnológico de Ciencias de la Salud, 18016 Granada, Spain.ORCID 0000-0003-1607-5106
Francisca VicenteFundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avenida del Conocimiento, 34 Parque Tecnológico de Ciencias de la Salud, 18016 Granada, Spain.ORCID 0000-0003-3198-9205
Olga Maria LageDepartment of Biology, Faculty of Sciences, University of Porto, Rua do Campo Alegre s/n, 4169-007 Porto, Portugal.
Universidade do Porto · PTFundación Medina · ES

Funding

Fundação para a Ciência e a Tecnologia SFRH/BD/145576/2019Fundação para a Ciência e a Tecnologia SFRH/BD/145577/2019Fundação para a Ciência e a Tecnologia UID/Multi/04423/2019
6 · The paper itself

Abstract

Oceans cover seventy percent of the planet's surface and besides being an immense reservoir of biological life, they serve as vital sources for human sustenance, tourism, transport and commerce. Yet, it is estimated by the National Oceanic and Atmospheric Administration (NOAA) that eighty percent of the oceans remain unexplored. The untapped biological resources present in oceans may be fundamental in solving several of the world's public health crises of the 21st century, which span from the rise of antibiotic resistance in bacteria, pathogenic fungi and parasites, to the rise of cancer incidence and viral infection outbreaks. In this review, health risks as well as how marine bacterial derived natural products may be tools to fight them will be discussed. Moreover, an overview will be made of the research pipeline of novel molecules, from identification of bioactive bacterial crude extracts to the isolation and chemical characterization of the molecules within the framework of the One Health approach. This review highlights information that has been published since 2014, showing the current relevance of marine bacteria for the discovery of novel natural products.

Indexed as

anticancerantimicrobial resistanceantimicrobialsantiviralsbioactive marine bacteriacancer incidencedrug discoverymarine natural productsOne Health

Identifiers

PMID32731464
PMCPMC7460513
OpenAlexW3045979239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.