Evidence map›Paper›PMID 32731418›Full record

ReviewMolecules (Basel, Switzerland)2020

Molecular Imaging of Fluorinated Probes for Tau Protein and Amyloid-β Detection.

Sarah K Yeo, Yurii Shepelytskyi, Vira Grynko, Mitchell S Albert

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Fluorinated Human Serum Albumin as PotentialMolecules (Basel, Switzerland) · 2023
    Article
  11. Article
  12. Article
  13. Cyclodextrin-Based Contrast Agents for Medical Imaging.Molecules (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sarah K YeoBiology Department, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.ORCID 0000-0003-0574-8168
Yurii ShepelytskyiChemistry and Materials Science Program, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.ORCID 0000-0001-5526-7958
Vira GrynkoChemistry and Materials Science Program, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.ORCID 0000-0002-9580-0072
Mitchell S AlbertThunder Bay Regional Health Research Institute, Thunder Bay, ON P7B 6V4, Canada.
Thunder Bay Regional Research Institute · CALakehead University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most common form of dementia and results in progressive neurodegeneration. The incidence rate of AD is increasing, creating a major public health issue. AD is characterized by neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau protein and senile plaques composed of amyloid-β (Aβ). Currently, a definitive diagnosis of AD is accomplished post-mortem. Thus, the use of molecular probes that are able to selectively bind to NFTs or Aβ can be valuable tools for the accurate and early diagnosis of AD. The aim of this review is to summarize and highlight fluorinated molecular probes that can be used for molecular imaging to detect either NFTs or Aβ. Specifically, fluorinated molecular probes used in conjunction with

Indexed as

Alzheimer DiseaseOptical ImagingPositron-Emission TomographyAmyloid beta-PeptidesHumansHydrocarbons, FluorinatedMolecular Probestau ProteinsAmyloid beta-PeptidesHydrocarbons, FluorinatedMAPT protein, humanMolecular Probestau ProteinsAlzheimer’s diseaseamyloid beta imagingfluorescencefluorinated molecular probesmolecular imagingMRIneurofibrillary tangle imagingPET

Identifiers

PMID32731418
PMCPMC7435578
OpenAlexW3045740973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.