Evidence map›Paper›PMID 32731342›Full record

ArticleAnimals : an open access journal from MDPI2020

Dietary Mannan Oligosaccharides Modulate Gut Inflammatory Response and Improve Duodenal Villi Height in Post-Weaning Piglets Improving Feed Efficiency.

Alessandro Agazzi, Vera Perricone, Fabio Omodei Zorini, Silvia Sandrini, Elena Mariani, Xian-Ren Jiang, Alessandra Ferrari, Maurizio Crestani, Thi Xuan Nguyen, Valentino Bontempo and 2 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 52 citations in OpenAlex.

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  17. The Role of YeastAnimals : an open access journal from MDPI · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Alessandro AgazziDepartment of Health, Animal Science and Food Safety "Carlo Cantoni" (VESPA), Università degli Studi di Milano, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0001-8285-7590
Vera PerriconeDepartment of Health, Animal Science and Food Safety "Carlo Cantoni" (VESPA), Università degli Studi di Milano, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0001-9477-2607
Fabio Omodei ZoriniDepartment of Health, Animal Science and Food Safety "Carlo Cantoni" (VESPA), Università degli Studi di Milano, Via dell'Università 6, 26900 Lodi, Italy.
Silvia SandriniDepartment of Health, Animal Science and Food Safety "Carlo Cantoni" (VESPA), Università degli Studi di Milano, Via dell'Università 6, 26900 Lodi, Italy.
Elena MarianiDipartimento di Scienze Medico-Veterinaire, Univeristy of Parma, Via del Taglio 10, 43126 Parma, Italy.ORCID 0000-0001-5855-6309
Xian-Ren JiangFeed Research Institute, Chinese Academy of Agricultural Sciences, Zhongguancun South Street 12, Beijing 100081, China.ORCID 0000-0002-8799-3572
Alessandra FerrariDepartment of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy.
Maurizio CrestaniDepartment of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy.ORCID 0000-0001-9230-1078
Thi Xuan NguyenDepartment of Health, Animal Science and Food Safety "Carlo Cantoni" (VESPA), Università degli Studi di Milano, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0001-6369-6816
Valentino BontempoDepartment of Health, Animal Science and Food Safety "Carlo Cantoni" (VESPA), Università degli Studi di Milano, Via dell'Università 6, 26900 Lodi, Italy.
Cinzia DomeneghiniDepartment of Health, Animal Science and Food Safety "Carlo Cantoni" (VESPA), Università degli Studi di Milano, Via dell'Università 6, 26900 Lodi, Italy.
Giovanni SavoiniDepartment of Health, Animal Science and Food Safety "Carlo Cantoni" (VESPA), Università degli Studi di Milano, Via dell'Università 6, 26900 Lodi, Italy.
University of Milan · ITChinese Academy of Agricultural Sciences · CNUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the effects of mannan oligosaccharides (MOS) on gut health and performance in post-weaning piglets. In total, 40 piglets were divided into two experimental groups and fed a basal diet with (TRT) or without (CON) 0.2% mannan oligosaccharides for 35 days. Growth performance was determined weekly and faecal microbial composition on days 0, 14 and 35. On day 36, histometrical evaluations were performed on duodenal, jejunal, ileal, and colon samples. mRNA gene expression of inflammation-related genes was evaluated in samples of ileal Peyer's patches (IPP). MOS administration improved feed efficiency in the last two weeks of the trial (

Indexed as

faecal microbiotagene expressiongut healthintestinal morphologymannan oligosaccharidespost-weaning piglets

Identifiers

PMID32731342
PMCPMC7459834
OpenAlexW3045043379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.