Evidence map›Paper›PMID 32730733›Full record

ArticleEmerging infectious diseases2020

Differential Tropism of SARS-CoV and SARS-CoV-2 in Bat Cells.

Susanna K P Lau, Antonio C P Wong, Hayes K H Luk, Kenneth S M Li, Joshua Fung, Zirong He, Flora K K Cheng, Tony T Y Chan, Stella Chu, Kam Leng Aw-Yong and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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  11. Emerging complexities of SARS-CoV-2 pandemic.Journal of family medicine and primary care · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Susanna K P Lau
Antonio C P Wong
Hayes K H Luk
Kenneth S M Li
Joshua Fung
Zirong He
Flora K K Cheng
Tony T Y Chan
Stella Chu
Kam Leng Aw-Yong
Terrence C K Lau
Kitty S C Fung
Patrick C Y Woo
City University of Hong Kong · HKUnited Christian Hospital · CNUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 did not replicate efficiently in 13 bat cell lines, whereas severe acute respiratory syndrome coronavirus replicated efficiently in kidney cells of its ancestral host, the Rhinolophus sinicus bat, suggesting different evolutionary origins. Structural modeling showed that RBD/RsACE2 binding may contribute to the differential cellular tropism.

Indexed as

AnimalsChiropteraCOVID-19HumansMiddle East Respiratory Syndrome CoronavirusPandemicsSARS-CoV-2Severe acute respiratory syndrome-related coronavirusViral TropismVirus Replicationbatcoronavirus diseaseCOVID-19originrespiratory infectionsSARSSARS-CoV-2SARS-related coronavirussevere acute respiratory syndromesevere acute respiratory syndrome coronavirus 2tropismviruseszoonoses

Identifiers

PMID32730733
PMCPMC7706959
OpenAlexW3046795692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.