Evidence map›Paper›PMID 32729984›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2020

Health-care use and cost for multimorbid persons with dementia in the National Health and Aging Trends Study.

Janet L MacNeil-Vroomen, Mary Thompson, Linda Leo-Summers, Richard A Marottoli, Ming Tai-Seale, Heather G Allore

Open access · greenAbstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Multimorbidity in dementia: Current perspectives and future challenges.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. U.S. dementia care spending by state: 2010-2019.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  12. Article
  13. Article
  14. Influence of Care Network Characteristics on Physician Visit Experiences for Black, White, and Hispanic Older Adults With Dementia.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023
    Article
  15. Article
  16. Cardiovascular disease and the risk of dementia: a survival analysis using administrative data from Manitoba.Canadian journal of public health = Revue canadienne de sante publique · 2022
    Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Janet L MacNeil-VroomenSection of Geriatrics, Department of Internal Medicine, School of Medicine, Yale University, New Haven, Connecticut, USA.
Mary ThompsonDepartment of Statistics and Actuarial Science, University of Waterloo, Waterloo, Canada.
Linda Leo-SummersSection of Geriatrics, Department of Internal Medicine, School of Medicine, Yale University, New Haven, Connecticut, USA.
Richard A MarottoliSection of Geriatrics, Department of Internal Medicine, School of Medicine, Yale University, New Haven, Connecticut, USA.
Ming Tai-SealeDepartment of Family Medicine and Public Health, School of Medicine, University of California San Diego, San Diego, California, USA.
Heather G AlloreSection of Geriatrics, Department of Internal Medicine, School of Medicine, Yale University, New Haven, Connecticut, USA.
Yale University · USUniversity of San Diego · USUniversity of Waterloo · CA

Funding

The National Health and Trends StudyU01AG032947 · NIA · JOHNS HOPKINS UNIVERSITY · PI VICKI A. FREEDMAN, JENNIFER ANN SCHRACK · 2008 to 2026
$169.4M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Albert C Shaw · 2002 to 2026
$37.9M
Yale Alzheimer Disease Research CenterP30AG066508 · NIA · YALE UNIVERSITY · PI STEPHEN M STRITTMATTER, CHRISTOPHER H VAN DYCK · 2020 to 2026
$30.2M
Yale Alzheimer Disease Research CenterP50AG047270 · NIA · YALE UNIVERSITY · PI MAROTTOLI, RICHARD · 2015 to 2019
$8.3M
Individualized Absolute Risk calculator For Persons With Multiple Chronic ConditionsR01AG047891 · NIA · YALE UNIVERSITY · PI ALLORE, HEATHER GWYNN · 2015 to 2017
$990k
NIA NIH HHS P30 AG021342NIA NIH HHS P30AG021342-16S1NIA NIH HHS P30 AG066508NIA NIH HHS P50 AG047270NIA NIH HHS P50AG047270NIA NIH HHS R01 AG047891NIA NIH HHS R01 AG047891-01A1NIA NIH HHS U01 AG032947
6 · The paper itself

Abstract

backgroundMost persons with dementia have multiple chronic conditions; however, it is unclear whether co-existing chronic conditions contribute to health-care use and cost.

methodsPersons with dementia and ≥2 chronic conditions using the National Health and Aging Trends Study and Medicare claims data, 2011 to 2014.

resultsChronic kidney disease and ischemic heart disease were significantly associated with increased adjusted risk ratios of annual hospitalizations, hospitalization costs, and direct medical costs. Depression, hypertension, and stroke or transient ischemic attack were associated with direct medical and societal costs, while atrial fibrillation was associated with increased hospital and direct medical costs. No chronic condition was associated with informal care costs.

conclusionsAmong older adults with dementia, proactive and ambulatory care that includes informal caregivers along with primary and specialty providers, may offer promise to decrease use and costs for chronic kidney disease, ischemic heart disease, atrial fibrillation, depression, and hypertension.

Indexed as

Cost of IllnessMultimorbidityPatient Acceptance of Health CareAgedChronic DiseaseDementiaFemaleHealth SurveysHeart DiseasesHospitalizationHumansInsurance Claim ReviewMaleMedicareUnited Statesdementiahealth utilizationlongitudinal studymultiple chronic conditionsNational Health and Aging Trends studypublic health

Identifiers

PMID32729984
PMCPMC9238348
OpenAlexW3046691819

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.