Evidence map›Paper›PMID 32729763›Full record

Trial reportNutrition and health2020

The effects of moderate alterations in adrenergic activity on acute appetite regulation in obese women: A randomised crossover trial.

Fotini Tsofliou, Yannis P Pitsiladis, Jose Lara, Marios Hadjicharalambous, Ian A Macdonald, Mike A Wallace, Mike E J Lean

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrition and health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Fotini TsofliouHuman Nutrition, School of Medicine, 3526University of Glasgow, United Kingdom.ORCID https://orcid.org/0000-0003-1605-5826
Yannis P PitsiladisCollege of Medical Veterinary and Life Science, Institute of Cardiovascular & Medical Sciences, 3526University of Glasgow, United Kingdom.
Jose LaraDepartment of Applied Sciences, Faculty of Health and Life Sciences, 5995Northumbria University, United Kingdom.
Marios HadjicharalambousCollege of Medical Veterinary and Life Science, Institute of Cardiovascular & Medical Sciences, 3526University of Glasgow, United Kingdom.
Ian A MacdonaldSchool of Life Sciences, 6123University of Nottingham Medical School, Queen's Medical Centre, United Kingdom.
Mike A WallaceUniversity Department of Pathological Biochemistry, Glasgow Royal Infirmary, United Kingdom.
Mike E J LeanHuman Nutrition, School of Medicine, 3526University of Glasgow, United Kingdom.
University of Glasgow · GBGlasgow Royal Infirmary · GBNorthumbria University · GBUniversity of Brighton · GBUniversity of Nicosia · CYUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious evidence has demonstrated that serum leptin is correlated with appetite in combination with, but not without, modest exercise.

aimThe present experiments investigated the effects of exogenous adrenaline and α/β adrenoceptor blockade in combination with moderate exercise on serum leptin concentrations, appetite/satiety sensations and subsequent food intake in obese women.

methodsA total of 10 obese women ((mean ± SEM), age: 50 (1.9) years, body mass index 36 (4.1) kg/m

resultsNo differences were found in appetite/satiety, subsequent food intake or serum leptin in any of the studies (experiment 1 or experiment 2). In experiment 1, blood glucose was higher (

conclusionsNeither inhibition of exercise-induced adrenergic activity by combined α/β adrenergic blockade nor moderate increases in adrenergic activity induced by intravenous adrenaline infusion affected acute appetite regulation.

Indexed as

ExerciseAdrenergic AgentsAdrenergic beta-AntagonistsAppetiteAppetite RegulationBlood GlucoseCross-Over StudiesDouble-Blind MethodEnergy IntakeEpinephrineFemaleHumansLabetalolLeptinMiddle AgedObesityAdrenergic AgentsAdrenergic beta-AntagonistsBlood GlucoseEpinephrineLabetalolLeptinadrenaline infusionadrenergic blockadeAppetite regulationmoderate exerciseobesity

Identifiers

PMID32729763
PMCPMC7534026
OpenAlexW3046407127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.