SynthesisHuman brain mapping2020
Can we predict real-time fMRI neurofeedback learning success from pretraining brain activity?
Synthesis in Human brain mapping, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Systematic review and meta-analysis of the relationships between real-time neurofeedback training parameters and acquisition of neural modulation.Frontiers in human neuroscience · 2025Pooled it
- Can we predict real-time fMRI neurofeedback learning success from pretraining brain activity?Human brain mapping · 2020Pooled it
- A systematic review of fMRI neurofeedback reporting and effects in clinical populations.NeuroImage. Clinical · 2020Pooled it
- The Potential of Functional Near-Infrared Spectroscopy-Based Neurofeedback-A Systematic Review and Recommendations for Best Practice.Frontiers in neuroscience · 2020Pooled it
- Psilocybin-assisted neurofeedback for the improvement of executive functions: a randomized semi-naturalistic-lab feasibility study.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Trial
- Double-Blind, Sham-Controlled Randomized Trial Testing the Efficacy of fMRI Neurofeedback on Clinical and Cognitive Measures in Children With ADHD.The American journal of psychiatry · 2022Trial
- Self-modulation of motor cortex activity after stroke: a randomized controlled trial.Brain : a journal of neurology · 2022Trial
- Neurofeedback in Football: A Systematic Review of Cognitive, Technical, Physical and Psychological Outcomes.NeuroSci · 2026Review
- The Impact of Visual Feedback Design on Self-Regulation Performance and Learning in a Single-Session rt-fMRI Neurofeedback Study at 3T and 7T.Brain sciences · 2026Article
- Neurofeedback: Applications, advancements, and future directions.PCN reports : psychiatry and clinical neurosciences · 2025Review
- Neural Mechanisms of Feedback Processing and Regulation Recalibration During Neurofeedback Training.Human brain mapping · 2025Article
- Real-time fMRI neurofeedback boosts heartbeat perception by modulating insula activation pattern during interoceptive attention.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Mechanisms of brain self-regulation: psychological factors, mechanistic models and neural substrates.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Regulation of craving for real-time fMRI neurofeedback based on individual classification.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- Amygdala self-neuromodulation capacity as a window for process-related network recruitment.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- Functional and structural connectivity success predictors of real-time fMRI neurofeedback targeting DLPFC: Contributions from central executive, salience, and default mode networks.Network neuroscience (Cambridge, Mass.) · 2024Article
- Functional near-infrared spectroscopy neurofeedback of dorsolateral prefrontal cortex enhances human spatial working memory.Neurophotonics · 2023Article
- Self-regulation learning as active inference: dynamic causal modeling of an fMRI neurofeedback task.Frontiers in neuroscience · 2023Article
- fMRI neurofeedback in the motor system elicits bidirectional changes in activity and in white matter structure in the adult human brain.Cell reports · 2021Article
- Putamen volume predicts real-time fMRI neurofeedback learning success across paradigms and neurofeedback target regions.Human brain mapping · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
39 authors.
Funding
Abstract
Neurofeedback training has been shown to influence behavior in healthy participants as well as to alleviate clinical symptoms in neurological, psychosomatic, and psychiatric patient populations. However, many real-time fMRI neurofeedback studies report large inter-individual differences in learning success. The factors that cause this vast variability between participants remain unknown and their identification could enhance treatment success. Thus, here we employed a meta-analytic approach including data from 24 different neurofeedback studies with a total of 401 participants, including 140 patients, to determine whether levels of activity in target brain regions during pretraining functional localizer or no-feedback runs (i.e., self-regulation in the absence of neurofeedback) could predict neurofeedback learning success. We observed a slightly positive correlation between pretraining activity levels during a functional localizer run and neurofeedback learning success, but we were not able to identify common brain-based success predictors across our diverse cohort of studies. Therefore, advances need to be made in finding robust models and measures of general neurofeedback learning, and in increasing the current study database to allow for investigating further factors that might influence neurofeedback learning.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.