Evidence map›Paper›PMID 32729495›Full record

ArticleBiosensors & bioelectronics2020

Graphene field-effect transistor biosensor for detection of biotin with ultrahigh sensitivity and specificity.

Shiyu Wang, Md Zakir Hossain, Kazuo Shinozuka, Natsuhiko Shimizu, Shunya Kitada, Takaaki Suzuki, Ryo Ichige, Anna Kuwana, Haruo Kobayashi

Open access · greenAbstract read
In one paragraph

Article in Biosensors & bioelectronics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 120 citations in OpenAlex.

  1. Article
  2. Review
  3. Contribution ofCurrent issues in molecular biology · 2025
    Review
  4. Article
  5. Recent Advances in Xenes Based FET for Biosensing Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Graphene-Oxide Peptide-Containing Materials for Biomedical Applications.International journal of molecular sciences · 2024
    Review
  11. 2D Materials in Advanced Electronic Biosensors for Point-of-Care Devices.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shiyu WangDivision of Electronics and Informatics, Graduate School of Science and Engineering, Gunma University 1-5-1 Tenjin-cho, Kiryu, 376-8515, Japan. Electronic address: t182d001@gunma-u.ac.jp.
Md Zakir HossainGunma University Initiative for Advanced Research (GIAR), Gunma University, Japan. Electronic address: zakir@gunma-u.ac.jp.
Kazuo ShinozukaDivision of Molecular Science, Graduate School of Science and Technology, Gunma University, Japan.
Natsuhiko ShimizuGunma University Initiative for Advanced Research (GIAR), Gunma University, Japan.
Shunya KitadaGunma University Initiative for Advanced Research (GIAR), Gunma University, Japan.
Takaaki SuzukiDivision of Mechanical Science and Technology, Gunma University, Kiryu, 376-8515, Japan.
Ryo IchigeDivision of Mechanical Science and Technology, Gunma University, Kiryu, 376-8515, Japan.
Anna KuwanaDivision of Electronics and Informatics, Graduate School of Science and Engineering, Gunma University 1-5-1 Tenjin-cho, Kiryu, 376-8515, Japan.
Haruo KobayashiDivision of Electronics and Informatics, Graduate School of Science and Engineering, Gunma University 1-5-1 Tenjin-cho, Kiryu, 376-8515, Japan. Electronic address: koba@gunma-u.ac.jp.
Gunma University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Because avidin and biotin molecules exhibit the most specific and strongest non-covalent interaction, avidin-biotin technology is widely used in ELISA (enzyme-linked immunosorbent assay) kits for the detection of different bio-macromolecules linked to different diseases including cancer and influenza. Combining the outstanding electrical conductivity (200,000 cm

Indexed as

Biosensing TechniquesGraphiteAvidinBiotinSensitivity and SpecificitySilicon DioxideAvidinBiotinGraphiteSilicon DioxideAvidinBiosensorBiotinClinical diagnosisField-effect transistorGraphene

Identifiers

PMID32729495
PMCPMC7272179
OpenAlexW3034172247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.