Evidence map›Paper›PMID 32729060›Full record

ArticleInternational ophthalmology2020

Inner retinal layers' alterations and microvasculature changes after vitrectomy for rhegmatogenous retinal detachment.

Irini Chatziralli, George Theodossiadis, Efstratios Parikakis, Alexandros Chatzirallis, Eleni Dimitriou, Panagiotis Theodossiadis

Abstract read
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In one paragraph

Article in International ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Irini Chatziralli2nd Department of Ophthalmology, University of Athens, 28, Papanastasiou Street, Alimos, 17342, Athens, Greece. eirchat@yahoo.gr.
George Theodossiadis2nd Department of Ophthalmology, University of Athens, 28, Papanastasiou Street, Alimos, 17342, Athens, Greece.
Efstratios Parikakis2nd Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece.
Alexandros Chatzirallis2nd Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece.
Eleni Dimitriou2nd Department of Ophthalmology, University of Athens, 28, Papanastasiou Street, Alimos, 17342, Athens, Greece.
Panagiotis Theodossiadis2nd Department of Ophthalmology, University of Athens, 28, Papanastasiou Street, Alimos, 17342, Athens, Greece.
National and Kapodistrian University of Athens · GRAthens Eye Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examine the retinal layers' changes and alterations in retinal microvasculature in patients with rhegmatogenous retinal detachment (RRD) treated with pars plana vitrectomy (PPV).

methodsParticipants in this study were 103 patients with RRD, 85 macula off and 18 macula on, who were treated with PPV and gas tamponade without internal limiting membrane peeling, in two centers. All participants underwent best corrected visual acuity measurement, slit-lamp examination, fundoscopy, spectral domain-optical coherence tomography and optical coherence tomography angiography at week 5 and at month 6 postoperatively. The fellow untreated eyes were also examined and served as control data.

resultsA statistically significant enlargement in foveal avascular zone (FAZ) in both superficial capillary plexus (SCP) and deep capillary plexus (DCP) was noticed 5 weeks postoperatively in patients with RRD treated with PPV compared to the fellow eyes and remained 6 months after surgery. The FAZ enlargement in the operated eyes was accompanied with a statistically significant thinning of the inner retinal layer. In addition, there was a significant decrease in foveal and parafoveal vessel density (VD) in both SCP and DCP in the operated eyes compared to control eyes at week 5 postoperatively, which also remained at postoperative month 6.

conclusionsThe study demonstrated that patients with RRD treated with PPV presented changes in the retinal microvasculature in both SCP and DCP, including enlargement of FAZ and decrease in VD. These changes seemed to be associated with inner retinal layer thinning.

Indexed as

Retinal DetachmentFluorescein AngiographyHumansMicrovesselsRetinal VesselsTomography, Optical CoherenceVisual AcuityVitrectomyInner retinal layerOCT angiographyRetinal microvasculatureRhegmatogenous retinal detachment

Identifiers

PMID32729060
OpenAlexW3045950649

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.