Evidence map›Paper›PMID 32729008›Full record

ReviewAdvances in therapy2020

Platelet Dysfunction Diseases and Conditions: Clinical Implications and Considerations.

Alan D Kaye, George M Jeha, Vanessa Moll, Ceressa T Ward, Matthew R Watson, John Thomas Wynn, Maxwell A Hockstein, Kevin M Hall, Omar Viswanath, Ivan Urits and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 2 countries.

Alan D KayeDepartment of Anesthesiology, LSU Health Shreveport, Shreveport, LA, USA.
George M JehaDepartment of Anesthesiology, LSU Health New Orleans, New Orleans, LA, USA.
Vanessa MollInstitute of Anesthesiology, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.
Ceressa T WardDepartment of Pharmacy, Emory University Hospital Midtown, Atlanta, GA, USA.
Matthew R WatsonDepartment of Pharmacy, Emory University Hospital Midtown, Atlanta, GA, USA.
John Thomas WynnEmory Critical Care Center, Emory University Hospital Midtown, Atlanta, GA, USA.
Maxwell A HocksteinDepartment of Anesthesia, Emory University School of Medicine, Atlanta, GA, USA.
Kevin M HallDepartment of Anesthesiology, Emory University Hospital Midtown, Atlanta, GA, USA.
Omar ViswanathValley Anesthesiology and Pain Consultants-Envision Physician Services, Phoenix, AZ, USA.
Ivan UritsDepartment of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Amit PrabhakarDivision of Critical Care, Department of Anesthesiology, Emory School of Medicine, Atlanta, GA, USA.
Elyse M CornettDepartment of Anesthesiology, LSU Health Shreveport, Shreveport, LA, USA. ecorne@lsuhsc.edu.
Emory University Hospital Midtown · USLouisiana State University Health Sciences Center Shreveport · USBeth Israel Deaconess Medical Center · USEmory and Henry College · USEmory University · USLouisiana State University Health Sciences Center New Orleans · USUniversity Hospital of Zurich · CHUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPlatelet diseases and dysfunction are taught early in medical school to all future physicians. Understanding of the coagulation cascade and hemostatic mechanisms has allowed for targeted pharmacological therapies that have been significantly impactful in clinical practice. Platelets are an early participant in hemostasis physiologically and under pathophysiological states.

methodsA review of literature involving platelet disfunction.

resultsVarious presentations of platelet diseases and dysfunction challenge clinicians and require a firm understanding of normal platelet function, drugs that mediate or modulate platelet effectiveness, and nonpharmacologic etiologies of platelet diseases and dysfunction with corresponding best practice treatment approaches.

conclusionThis review summarizes normal and abnormal states associated with platelets and treatment strategies.

Indexed as

AdultAgedAged, 80 and overBlood Platelet DisordersFemaleHemostasisHumansMaleMiddle AgedHemostasisPlatelet disfunctionSystemic lupus erythematosusThrombotic thrombocytopenic purpura

Identifiers

PMID32729008
OpenAlexW3046068037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.