Evidence map›Paper›PMID 32728960›Full record

Observational studyJournal of general internal medicine2020

Impact of Instrumental Activities of Daily Living Limitations on Hospital Readmission: an Observational Study Using Machine Learning.

Nicholas K Schiltz, Mary A Dolansky, David F Warner, Kurt C Stange, Stefan Gravenstein, Siran M Koroukian

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Journal of general internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Early Occupational Therapy Intervention in the Hospital Discharge after Stroke.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Nicholas K SchiltzFrances Payne Bolton School of Nursing , Case Western Reserve University, 10900 Euclid Avenue, Room 459H, Cleveland, OH, 44106-7343, USA. nks8@case.edu.ORCID http://orcid.org/0000-0003-0122-6477
Mary A DolanskyFrances Payne Bolton School of Nursing , Case Western Reserve University, 10900 Euclid Avenue, Room 459H, Cleveland, OH, 44106-7343, USA.
David F WarnerDepartment of Sociology, University of Alabama at Birmingham, Birmingham, AL, USA.
Kurt C StangeDepartment of Population & Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Stefan GravensteinDepartment of Health Services, Policy, and Practice, Brown University, Providence, RI, USA.
Siran M KoroukianDepartment of Population & Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Case Western Reserve University · USProvidence College · USUniversity of Alabama at Birmingham · US

Funding

TUMOR METABOLISM PROGRAMP30CA043703 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI MARK R CHANCE · 1987 to 2026
$142.3M
Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Clinical and Translational Science Collaborative of ClevelandUL1TR002548 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2018 to 2022
$35.5M
Institutional Career Development CoreKL2TR002547 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI DWEIK, RAED A. · 2018 to 2022
$7.7M
Prevention Research Center for Healthy NeighborhoodsU48DP005030 · DP · CASE WESTERN RESERVE UNIVERSITY · PI BORAWSKI, ELAINE A. · 2014 to 2018
$6.8M
Multi-Level Interventions to Reduce Caries Disparities in Primary Care SettingsUH3DE025487 · NIDCR · CASE WESTERN RESERVE UNIVERSITY · PI NELSON, SUCHITRA S. · 2017 to 2021
$5.6M
Identifying Electronic Phenotypes associated with Patient Health Outcomes of Interhospital Transfer PatientsR15NR017792 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI REIMER, ANDREW PAUL · 2018 to 2018
$477k
Combination of chronic conditions determining clinical relevance and resource useR21HS023113 · AHRQ · CASE WESTERN RESERVE UNIVERSITY · PI KOROUKIAN, SIRAN M. · 2014 to 2014
$179k
AHRQ HHS R21 HS023113NCATS NIH HHS KL2 TR002547NCATS NIH HHS UL1 TR000439NCATS NIH HHS UL1 TR002548NCCDPHP CDC HHS U48 DP005030NCI NIH HHS P30 CA043703NIDCR NIH HHS UH3 DE025487NINR NIH HHS R15 NR017792
6 · The paper itself

Abstract

backgroundLimitations in instrumental activities of daily living (IADL) hinder a person's ability to live independently in the community and self-manage their conditions, but its impact on hospital readmission has not been firmly established.

objectiveTo test the importance of IADL dependency as a predictor of 30-day readmissions and quantify its impact relative to other morbidities.

designA retrospective cohort study of the population-based Health and Retirement Study linked to Medicare claims data. Random forest was used to rank each predictor variable in terms of its ability to predict readmission. Classification and regression tree (CART) was used to identify complex multimorbidity combinations associated with high or low risk of readmission. Generalized linear regression was used to estimate the adjusted relative risk of readmission for IADL limitations. SUBJECTS: Hospitalizations of adults age 65 and older (n = 20,007), from 6617 unique subjects. MAIN MEASURES: The main outcome was 30-day all-cause unplanned readmission. The main predictor of interest was self-reported IADL limitation. Other key predictors were self-reported complex multimorbidity including chronic diseases, geriatric syndromes, and activities of daily living (ADL) limitations, along with demographic, socioeconomic, and behavioral factors. KEY

resultsThe overall 30-day readmission rate in the study was 16.4%. Random forest analysis ranked ADLs and IADL limitations as the two most important predictors of 30-day readmission. CART identified hospitalizations of patients with IADL limitations and diabetes as a subgroup at the highest risk of readmission (26% readmitted). Multivariable regression analyses showed that ADL limitations were associated with 1.17 (1.06-1.29) times higher risk of readmission even after adjusting for other patient covariates. Risk prediction was modest though for even the best model (AUC = 0.612).

conclusionsIADL limitations are key predictors of 30-day readmission as demonstrated using several machine learning methods. Routine assessment of functional abilities in hospital settings could help identify those most at risk.

Indexed as

Activities of Daily LivingPatient ReadmissionAgedHumansMachine LearningMedicareRetrospective StudiesUnited Statesactivities of daily livinghealth services researchmultimorbiditypatient readmissionsupervised machine learning

Identifiers

PMID32728960
PMCPMC7573020
OpenAlexW3046192699

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.