Evidence map›Paper›PMID 32728801›Full record

Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

The perception gap of chemotherapy-induced adverse events between doctors and cancer patients: an observational study in China.

Juan Yu, Zhen Zhang, Huaqiang Zhou, Xia Liu, Yan Huang, Wenfeng Fang, Yunpeng Yang, Shaodong Hong, Ting Zhou, Yaxiong Zhang and 7 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Juan Yu *Department of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, China.
Zhen Zhang *Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.ORCID http://orcid.org/0000-0002-1840-3110
Huaqiang Zhou *Department of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, China.
Xia Liu *Department of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, China.
Yan HuangDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, China.
Wenfeng FangDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, China.
Yunpeng YangDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, China.
Shaodong HongDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, China.
Ting ZhouDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, China.
Yaxiong ZhangDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, China.
Gang ChenDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, China.
Shen ZhaoDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, China.
Zhonghan ZhangDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, China.
Yuxiang MaState Key Laboratory of Oncology in South China, Guangzhou, China.
Hongyun ZhaoState Key Laboratory of Oncology in South China, Guangzhou, China.
Ruizhen GaoDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, China. gaorzh@sysucc.org.cn.
Li ZhangDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, China. zhangli6@mail.sysu.edu.cn.

Funding

Medical Scientific Research Foundation of Guangdong Province A2020153Medical Scientific Research Foundation of Guangdong Province C2018062Science and Technology Program of Guangzhou 201704020072the National Key R&D Program of China 2016YFC0905500the National Key R&D Program of China 2016YFC0905503
6 · The paper itself

Abstract

introductionPatient-reported outcomes (PROs) have been widely accepted in western countries. However, limited attention has been given to PROs in China due to a lack of research on the agreement between doctors' and patients' reports of adverse events. This study aims to reveal the perception gap of chemotherapy-induced adverse events between doctors and cancer patients in China.

methodsAn observational study was administered at Sun Yat-Sen University Cancer Center (SYSUCC). Totally, 200 adult cancer patients undergoing chemotherapy participated. Patient reports were collected by nurses via telephone. Doctor reports were collected by nurses based on their medical records. The agreement between doctors and patients was analyzed by Cohen's κ.

resultsAgreement between doctors and patients varied among different symptoms: 0.26 for nausea/vomiting, 0.49 for constipation, 0.63 for diarrhea, 0.65 for general pain, and 0.76 for rash. Doctors' underreporting rates were 70% for nausea/vomiting, 50% for diarrhea, 38% for rash, 33% for constipation, and 29% for general pain.

conclusionsThe perception gap of chemotherapy-induced adverse events between doctors and patients exists in China, especially regarding subjective symptoms. Introduction of PROs in both clinical trials and routine clinical practice should be considered in China.

Indexed as

Patient Reported Outcome MeasuresAntineoplastic AgentsChinaFemaleHumansMaleMiddle AgedPatientsPerceptionPhysiciansAntineoplastic AgentsChemotherapyChinaPatient reported outcomesperception gap

Identifiers

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.