ArticleCerebral cortex (New York, N.Y. : 1991)2020
Mapping Human Laryngeal Motor Cortex during Vocalization.
Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.
- Can MRI measure myelin? Systematic review, qualitative assessment, and meta-analysis of studies validating microstructural imaging with myelin histology.NeuroImage · 2021Pooled it
- Functional neuroplasticity in chronic post-stroke aphasia following a singing intervention in a cross-over randomised trial.Scientific reports · 2025Trial
- Encoding of speech modes and loudness in ventral precentral gyrus.Nature communications · 2026Article
- Unifying the gestural and the vocal in the evolution of culture, the arts, and the brain.Frontiers in psychology · 2026Article
- Speech sequencing in the human precentral gyrus.Nature human behaviour · 2025Article
- Causal Lesion Evidence for Two Motor Speech Coordination Networks in the Brain.bioRxiv : the preprint server for biology · 2025Article
- Encoding of speech modes and loudness in ventral precentral gyrus.bioRxiv : the preprint server for biology · 2025Article
- Article
- Invasive Brain-Computer Interface for Communication: A Scoping Review.Brain sciences · 2025Review
- Dissecting the Causal Role of Early Inferior Frontal Activation in Reading.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The Effects of Theta-Gamma Peak Stimulation on Sensorimotor Learning During Speech Production.Neurobiology of language (Cambridge, Mass.) · 2025Article
- The cost of language: functionally over-dominant language circuits in the human brain may limit cognitive abilities and non-verbal executive functions.Frontiers in human neuroscience · 2025Article
- Vocal Cord Palsy in Hypoxic Brain Injury: A Qualitative Systematic Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- The speech neuroprosthesis.Nature reviews. Neuroscience · 2024Review
- The mouse motor system contains multiple premotor areas and partially follows human organizational principles.Cell reports · 2024Article
- Neural basis of speech and grammar symptoms in non-fluent variant primary progressive aphasia spectrum.Brain : a journal of neurology · 2024Article
- Knowns and unknowns about the neurobiology of stuttering.PLoS biology · 2024Article
- Decoding kinematic information from beta-band motor rhythms of speech motor cortex: a methodological/analytic approach using concurrent speech movement tracking and magnetoencephalography.Frontiers in human neuroscience · 2024Article
- Impairment of the internal forward model and feedback mechanisms for vocal sensorimotor control in post-stroke aphasia: evidence from directional responses to altered auditory feedback.Experimental brain research · 2024Article
- Volitional inspiration is mediated by two independent output channels in the primary motor cortex.The Journal of comparative neurology · 2023Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
The representations of the articulators involved in human speech production are organized somatotopically in primary motor cortex. The neural representation of the larynx, however, remains debated. Both a dorsal and a ventral larynx representation have been previously described. It is unknown, however, whether both representations are located in primary motor cortex. Here, we mapped the motor representations of the human larynx using functional magnetic resonance imaging and characterized the cortical microstructure underlying the activated regions. We isolated brain activity related to laryngeal activity during vocalization while controlling for breathing. We also mapped the articulators (the lips and tongue) and the hand area. We found two separate activations during vocalization-a dorsal and a ventral larynx representation. Structural and quantitative neuroimaging revealed that myelin content and cortical thickness underlying the dorsal, but not the ventral larynx representation, are similar to those of other primary motor representations. This finding confirms that the dorsal larynx representation is located in primary motor cortex and that the ventral one is not. We further speculate that the location of the ventral larynx representation is in premotor cortex, as seen in other primates. It remains unclear, however, whether and how these two representations differentially contribute to laryngeal motor control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.