ArticlePeerJ2020
Arthropod IGF, relaxin and gonadulin, putative orthologs of
Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 59 citations in OpenAlex.
- Ontogenetic Sequence of Differential Gene Expression in Predator-Induced Daphnia pulex.Molecular ecology · 2026Article
- An insulin-like peptide mediates trehalose storage in the western tarnished plant bug, Lygus hesperus.Journal of insect physiology · 2025Article
- What comparative endocrinology tells us about the original function of the insulin superfamily.Endocrine journal · 2025Review
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- Article
- Functions of Insulin-like Peptide Genes (Insects · 2024Article
- Identification and Characterization of a Novel Insulin-like Receptor (Biomolecules · 2024Article
- The diverse roles of insulin signaling in insect behavior.Frontiers in insect science · 2024Review
- Insulin-like peptides and ovary ecdysteroidogenic hormone differentially stimulate physiological processes regulating egg formation in the mosquito Aedes aegypti.Insect biochemistry and molecular biology · 2023Article
- Evolution of a Cockroach Allergen into the Major Protein of Termite Royal Jelly.International journal of molecular sciences · 2023Article
- Diapause-Linked Gene Expression Pattern and Related Candidate Duplicated Genes of the Mountain ButterflyInternational journal of molecular sciences · 2023Article
- Insulin peptides and their receptors regulate ovarian development and oviposition behavior in Diaphorina citri.Insect science · 2023Article
- Insulin-like peptide 8 (Ilp8) regulates female fecundity in flies.Frontiers in cell and developmental biology · 2023Article
- Article
- Crosstalk between Nutrition, Insulin, Juvenile Hormone, and Ecdysteroid Signaling in the Classical Insect Model,International journal of molecular sciences · 2022Article
- Neuropeptidomes ofJournal of proteome research · 2022Article
- Neuropeptides in Rhipicephalus microplus and other hard ticks.Ticks and tick-borne diseases · 2022Article
- Amphioxus muscle transcriptomes reveal vertebrate-like myoblast fusion genes and a highly conserved role of insulin signalling in the metabolism of muscle.BMC genomics · 2022Article
- Insects as a New Complex Model in Hormonal Basis of Obesity.International journal of molecular sciences · 2021Review
- Identification of Gonadulin and Insulin-Like Growth Factor From Migratory Locusts and Their Importance in Reproduction inFrontiers in endocrinology · 2021Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInsects have several genes coding for insulin-like peptides and they have been particularly well studied in METHODOLOGY: In an effort to identify gonadulins in other arthropods public genome assemblies and short-read archives from insects and other arthropods were explored for the presence of genes and transcripts coding insulin-like peptides and their putative receptors.
resultsGonadulins were detected in a number of arthropods. In those species for which transcriptome data from the gonads is available insect gonadulin genes are expressed in the ovaries and at least in some species also in the testes. In some insects differences in gonadulin expression in the ovary between actively reproducing and non-reproducing females differs more than 100-fold. Putative orthologs of
conclusionA local gene triplication in an early ancestor likely yielded three genes coding gonadulin, arthropod insulin-like growth factor and relaxin. Orthologs of these genes are now commonly present in arthropods and almost certainly include the
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.