Evidence map›Paper›PMID 32728494›Full record

ArticlePeerJ2020

Association between individual retinal layer thickness and visual acuity in patients with epiretinal membrane: a pilot study.

Jing Zou, Wei Tan, Wenlong Huang, Kangcheng Liu, Fangling Li, Huizhuo Xu

Abstract read
In one paragraph

Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. 3D volumetric analysis outperforms 2D linear measurements in predicting vision after surgery for epiretinal membranes. An exploratory machine learning study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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  11. Correlation between tangential distortion of the outer retinal layer and metamorphopsia in patients with epiretinal membrane.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing Zou *Eye Center of Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Wei Tan *Eye Center of Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Wenlong HuangEye Center of Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Kangcheng LiuEye Center of Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Fangling LiEye Center of Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Huizhuo XuEye Center of Xiangya Hospital, Central South University, Changsha, Hunan Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe investigated the correlation between visual acuity (VA) and individual retinal layer thickness in the foveal, parafoveal, and perifoveal regions of patients with an idiopathic epiretinal membrane (ERM).

methodsOne hundred and five subjects presenting with unilateral idiopathic ERM were included in this study. We segmented each patient's optical coherence tomography (OCT) image into seven layers and calculated the mean layer thickness in the foveal, parafoveal, and perifoveal regions using the Iowa Reference Algorithm. In 105 patients with ERM, we detected correlations between their macular regions' individual retinal layer thickness and their best corrected VA. Thirty-one of the 105 patients with ERM underwent vitrectomy and completed six months of follow-up. We then compared the 31 surgical patients' preoperative and postoperative individual retinal layer thickness in each macular region. Additionally, the association between preoperative individual retinal layer thickness in each macular region and VA six months post-surgery in patients with ≥ two Snellen lines of visual improvement was determined.

resultsMultiple linear regression analysis showed that the inner nuclear layer (INL) thickness in the foveal, parafoveal, and perifoveal region were all associated with VA in the 105 patients (

conclusionWe detected a correlation between retinal damage and VA in the parafoveal, perifoveal, and foveal regions. Our results suggest that INL thickness in all macular regions may be a prognostic factor for postoperative VA in ERM patients.

Indexed as

Epiretinal membraneFoveal regionParafoveal regionPerifoveal regionRetinal layer thicknessVisual acuity

Identifiers

PMID32728494
PMCPMC7357566

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.