Evidence map›Paper›PMID 32728478›Full record

ArticleNature reviews. Materials2020

Multifunctional materials for implantable and wearable photonic healthcare devices.

Geon-Hui Lee, Hanul Moon, Hyemin Kim, Gae Hwang Lee, Woosung Kwon, Seunghyup Yoo, David Myung, Seok Hyun Yun, Zhenan Bao, Sei Kwang Hahn

Open access · greenAbstract read
In one paragraph

Article in Nature reviews. Materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed
43.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 645 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Photonic Nanomaterials for Wearable Health Solutions.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Wearable bioelectronics for cancer theranostics.Microsystems & nanoengineering · 2025
    Review
  19. Review
  20. Article

77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Geon-Hui LeeDepartment of Materials Science and Engineering, Pohang University of Science and Technology (POSTECH), Pohang, South Korea.
Hanul MoonDepartment of Chemical Engineering, Stanford University, Stanford, CA, USA.
Hyemin KimPHI Biomed Co., Seoul, South Korea.
Gae Hwang LeeDepartment of Chemical Engineering, Stanford University, Stanford, CA, USA.
Woosung KwonDepartment of Chemical and Biological Engineering, Sookmyung Women's University, Seoul, South Korea.
Seunghyup YooSchool of Electrical Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea.
David MyungDepartment of Chemical Engineering, Stanford University, Stanford, CA, USA.
Seok Hyun YunWellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-8903-5909
Zhenan BaoDepartment of Chemical Engineering, Stanford University, Stanford, CA, USA.ORCID 0000-0002-0972-1715
Sei Kwang HahnDepartment of Materials Science and Engineering, Pohang University of Science and Technology (POSTECH), Pohang, South Korea.ORCID 0000-0002-7718-6259
Pohang University of Science and Technology · KRKorea Advanced Institute of Science and Technology · KRHanalei Watershed Hui · USHarvard University · USSmith-Kettlewell Eye Research Institute · USSookmyung Women's University · KRStanford University · US

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AAKALU, VINAY · 1985 to 2025
$14.8M
Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
NEI NIH HHS P30 EY001792NEI NIH HHS P30 EY026877
6 · The paper itself

Abstract

Numerous light-based diagnostic and therapeutic devices are routinely used in the clinic. These devices have a familiar look as items plugged in the wall or placed at patients' bedsides, but recently, many new ideas have been proposed for the realization of implantable or wearable functional devices. Many advances are being fuelled by the development of multifunctional materials for photonic healthcare devices. However, the finite depth of light penetration in the body is still a serious constraint for their clinical applications. In this Review, we discuss the basic concepts and some examples of state-of-the-art implantable and wearable photonic healthcare devices for diagnostic and therapeutic applications. First, we describe emerging multifunctional materials critical to the advent of next-generation implantable and wearable photonic healthcare devices and discuss the path for their clinical translation. Then, we examine implantable photonic healthcare devices in terms of their properties and diagnostic and therapeutic functions. We next describe exemplary cases of noninvasive, wearable photonic healthcare devices across different anatomical applications. Finally, we discuss the future research directions for the field, in particular regarding mobile healthcare and personalized medicine.

Identifiers

PMID32728478
PMCPMC7388681
OpenAlexW2999240275

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.