Evidence map›Paper›PMID 32728350›Full record

ArticleJournal of interventional cardiology2020

Mechanical and Pharmacological Revascularization Strategies for Prevention of Microvascular Dysfunction in ST-Segment Elevation Myocardial Infarction: Analysis from Index of Microcirculatory Resistance Registry Data.

Ji-Hun Jang, Man-Jong Lee, Kyu-Yong Ko, Jin-Hee Park, Yong-Soo Baek, Kwon Sung-Woo, Sung-Hee Shin, Seong-Ill Woo, Dae-Hyeok Kim, Young Ju Suh and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of interventional cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Ji-Hun JangDivision of Cardiology, Department of Internal Medicine, Inha University Hospital, Incheon, Republic of Korea.
Man-Jong LeeDivision of Cardiology, Department of Internal Medicine, Inha University Hospital, Incheon, Republic of Korea.
Kyu-Yong KoDivision of Cardiology, Department of Internal Medicine, Inha University Hospital, Incheon, Republic of Korea.
Jin-Hee ParkDivision of Cardiology, Department of Internal Medicine, Inha University Hospital, Incheon, Republic of Korea.
Yong-Soo BaekDivision of Cardiology, Department of Internal Medicine, Inha University Hospital, Incheon, Republic of Korea.
Kwon Sung-WooDivision of Cardiology, Department of Internal Medicine, Inha University Hospital, Incheon, Republic of Korea.
Sung-Hee ShinDivision of Cardiology, Department of Internal Medicine, Inha University Hospital, Incheon, Republic of Korea.
Seong-Ill WooDivision of Cardiology, Department of Internal Medicine, Inha University Hospital, Incheon, Republic of Korea.
Dae-Hyeok KimDivision of Cardiology, Department of Internal Medicine, Inha University Hospital, Incheon, Republic of Korea.
Young Ju SuhDepartment of Biomedical Sciences, Inha University Hospital, Inha University School of Medicine, Incheon, Republic of Korea.
Jun KwanDivision of Cardiology, Department of Internal Medicine, Inha University Hospital, Incheon, Republic of Korea.
Sang-Don ParkDivision of Cardiology, Department of Internal Medicine, Inha University Hospital, Incheon, Republic of Korea.ORCID https://orcid.org/0000-0003-0128-9988
Inha University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe aimed to identify mechanical and pharmacological revascularization strategies correlated with the index of microcirculatory resistance (IMR) in ST-elevation myocardial infarction (STEMI) patients.

backgroundMicrovascular dysfunction (MVD) after STEMI is correlated with infarct size and poor long-term prognosis, and the IMR is a useful analytical method for the quantitative assessment of MVD. However, therapeutic strategies that can reliably reduce MVD remain uncertain.

methodsPatients with STEMI who underwent primary percutaneous coronary intervention (PCI) were enrolled. The IMR was measured with a pressure sensor/thermistor-tipped guidewire immediately after primary PCI. High IMR was defined as values ≥66

resultsA total of 160 STEMI patients were analyzed (high IMR = 54 patients). Clinical factors for Killip class (

conclusionsIn our study, mechanical strategies were suboptimal in achieving myocardial salvage. Preloading of third-generation P2Y12 inhibitors revealed decreased IMR value, indicative of MVD prevention.

Indexed as

Percutaneous Coronary InterventionPostoperative ComplicationsST Elevation Myocardial InfarctionCoronary AngiographyCoronary CirculationFemaleHumansMaleMicrocirculationMiddle AgedOutcome and Process Assessment, Health CarePlatelet Aggregation InhibitorsPurinergic P2Y Receptor AntagonistsSecondary PreventionStentsThrombectomyPlatelet Aggregation InhibitorsPurinergic P2Y Receptor Antagonists

Identifiers

PMID32728350
PMCPMC7368229
OpenAlexW3040930431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.