ArticleNature2020
The changing mouse embryo transcriptome at whole tissue and single-cell resolution.
Abstract read
In one paragraph
Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.
0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
107 citing papers in PubMed.
- Metabolism of citrate-mediated PI3K-Akt signaling and primary cilium regulates spatiotemporal craniofacial mineralization.Bioactive materials · 2026Article
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- A targeted triple-action redox-modulating hydrogel potentiates fibroblast-mediated repair to accelerate oral wound healing.Materials today. Bio · 2026Article
- Transcriptomic Analysis Reveals Multilayer Regulation Underlying Development and Pregnancy in the Malayan Pangolin.Animal genetics · 2026Article
- Evolution of limb and digit identity genes since the tetrapod ancestor.Nature communications · 2026Article
- Metadomain and metaloop genome interactions in mammalian T cells.Cell reports · 2026Article
- RegFormer: a single-cell foundation model powered by gene regulatory hierarchies.Nature communications · 2026Article
- Type E endothelial cells orchestrate embryonic skeletogenesis via chondrogenic priming of skeletal progenitors.Journal of orthopaedic translation · 2026Article
- Chromatin-intrinsic mechanisms determine orientation-specific class switch recombination.Nature communications · 2026Article
- Benchmarking LLM-based agents for single-cell omics analysis.Genome biology · 2026Article
- Profiling the epigenomic landscape of late embryonic and adult mouse hind limb muscles.Scientific reports · 2026Article
- DLX2 acts as a pioneer factor and drivesScience advances · 2026Article
- Temporal constraints on enhancer usage shape the regulation of limb gene transcription.Nature communications · 2026Article
- Ancestral intronic splicing regulatory elements in the SCNbioRxiv : the preprint server for biology · 2026Article
- Reconstructing epigenomic dynamics through a single-cell multi-epigenome data integration framework.Nature communications · 2025Article
- Accurate and robust 3D genome feature discovery from multiplexed DNA FISH.bioRxiv : the preprint server for biology · 2025Article
- Metabolomic landscape of fetal organ development during late gestation in mice.Communications biology · 2025Article
- EHMT2 Controls Neural Crest-Derived Craniofacial Development but is Dispensable in Limb Development.bioRxiv : the preprint server for biology · 2025Article
- A patient-derived organoid model captures fetal-like plasticity in colorectal cancer.Cell research · 2025Article
47 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Peng He *Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.ORCID http://orcid.org/0000-0002-2457-3554
Brian A Williams *Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. bawilli@caltech.edu.ORCID http://orcid.org/0000-0003-3253-611X
Diane TroutDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.ORCID http://orcid.org/0000-0002-4928-5532
Georgi K MarinovDepartment of Genetics, Stanford University, Palo Alto, CA, USA.
Henry AmrheinDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Libera BerghellaDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Say-Tar GohDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Ingrid Plajzer-FrickEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Veena AfzalEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Len A PennacchioEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.ORCID http://orcid.org/0000-0002-8748-3732
Diane E DickelEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-5497-6824
Axel ViselEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.ORCID http://orcid.org/0000-0002-4130-7784
Bing RenDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-5435-1127
Ross C HardisonDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA, USA.ORCID http://orcid.org/0000-0003-4084-7516
Yu ZhangDepartment of Statistics, Pennsylvania State University, University Park, PA, USA.
Barbara J WoldDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. bjwold@caltech.edu.ORCID http://orcid.org/0000-0003-3235-8130
Funding
Toward a comprehensive functional annotation of the human genomeU54HG006998 · NHGRI · HUDSON-ALPHA INSTITUTE FOR BIOTECHNOLOGY · PI MYERS, RICHARD M · 2012 to 2016
$17.5MHigher Precision Human and Mouse TranscriptomesUM1HG009443 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI MORTAZAVI, SEYED ALI, WOLD, BARBARA J · 2017 to 2021
$15.5MCenter for Mammalian Regulatory GenomicsU54HG006997 · NHGRI · LUDWIG INSTITUTE FOR CANCER RES LTD · PI REN, BING · 2012 to 2016
$14.3MVISION: ValIdated Systematic IntegratiON of epigenomic dataR24DK106766 · NIDDK · PENNSYLVANIA STATE UNIVERSITY, THE · PI BLOBEL, GERD A, BODINE, DAVID M. · 2016 to 2020
$6.2MA 2D segmentation method for jointly characterizing epigenetic dynamics in multiple cell linesR01GM121613 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI MAHONY, SHAUN AENGUS · 2017 to 2019
$1.0MNHGRI NIH HHS U54 HG006997NHGRI NIH HHS U54 HG006998NHGRI NIH HHS UM1 HG009443NIDDK NIH HHS R24 DK106766NIGMS NIH HHS R01 GM121613
Abstract
During mammalian embryogenesis, differential gene expression gradually builds the identity and complexity of each tissue and organ system
Indexed as
Gene Expression Regulation, DevelopmentalSingle-Cell AnalysisTranscriptomeAnimalsCell DifferentiationCell LineageChromatinEmbryo, MammalianEmbryonic DevelopmentEnhancer Elements, GeneticEpigenomicsExtremitiesFemaleMaleMicePoly AChromatinPoly ATranscription Factors
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.