ArticleNature2020
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In one paragraph
Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed, 1 pooled it
11.5field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
129 citing papers in PubMed, 1 synthesis or guideline pooled it, 228 citations in OpenAlex.
- Rejuvenation of Bone Marrow Mesenchymal Stem Cells: Mechanisms and Their Application in Senile Osteoporosis Treatment.Biomolecules · 2025Pooled it
- Hypoxia Triggers BNIP3/BNIP3L-Associated Mitophagy in HT22 Immortalized Hippocampal Neurons: A Temporal Descriptive Study.Biology · 2026Article
- Experimental workflows for the accurate identification of mitochondrial redox events.Redox biology · 2026Review
- A ratiometric fluorescent reporter of mitochondrial sodium.Nature chemical biology · 2026Article
- Review
- Compatibility of Acorus tatarinowii Schott and Polygala tenuifolia Willd. alleviate Alzheimer's disease through regulating Nos2-mediated calcium signaling pathway.Neurochemical research · 2026Article
- MICU proteins facilitate calcium-dependent mitochondrial metabolon formation to regulate cellular energetics independently of MCU.Nature metabolism · 2026Article
- All-Dielectric Metasurface-Enhanced Fluorescence for Probing Mitochondrial Membrane Potential Dynamics.Chemical & biomedical imaging · 2026Article
- Disruption of sphingolipid metabolism triggers lung vascular inflammation and aging-like changes under hypoxia through VDAC1-mediated mitochondrial DNA release.Apoptosis : an international journal on programmed cell death · 2026Article
- Mitochondrial Calcium Signaling in Hepatocyte Health and Disease.Cold Spring Harbor perspectives in biology · 2026Review
- Spatiotemporal dynamics of reactive oxygen species: implications for cellular homeostasis and redox therapies.Cellular & molecular biology letters · 2026Review
- A Brief Description of the Cellular Mechanisms Involved in Cardiac Chemical Hypoxia.Cardiovascular toxicology · 2026Review
- Bioenergetic profiles and respiratory control in mitochondrial physiology: Precision analysis of oxidative phosphorylation.Experimental physiology · 2026Article
- Sodium disrupts mitochondrial energy metabolism to execute NECSO.Nature communications · 2025Article
- Mitochondrial Permeability Transition Pore: The Cardiovascular Disease's Molecular Achilles Heel.Biomedicines · 2025Review
- Rac1 promotes proximal tubule kidney repair by coupling the actin cytoskeleton to mitochondrial function.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Modulating mitochondrial metabolism: a neuroprotective mechanism for hypoxic-ischemic preconditioning.Cell regeneration (London, England) · 2025Review
- The Role of Reactive Oxygen Species (ROS) in Periodontitis: A Potential Therapeutic Target.Immunity, inflammation and disease · 2025Review
- Calcium signaling hypothesis: A non-negligible pathogenesis in Alzheimer's disease.Journal of advanced research · 2025Review
- Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology.Nature metabolism · 2025Article
69 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors at 10 institutions in 3 countries.
Pablo Hernansanz-AgustínUnidad de Investigación, Hospital Universitario Santa Cristina, Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain.
Carmen Choya-FocesUnidad de Investigación, Hospital Universitario Santa Cristina, Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain.
Susana Carregal-RomeroCenter for Cooperative Research in Biomaterials (CIC biomaGUNE), Basque Research and Technology Alliance (BRTA), Donostia San Sebastián, Spain.ORCID http://orcid.org/0000-0003-1444-6268
Elena RamosServicio de Inmunología, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain.
Tamara OlivaUnidad de Investigación, Hospital Universitario Santa Cristina, Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain.
Tamara Villa-PiñaServicio de Inmunología, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain.
Laura MorenoCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain.ORCID http://orcid.org/0000-0001-9028-2299
Alicia Izquierdo-ÁlvarezServicio de Inmunología, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain.
J Daniel Cabrera-GarcíaUnidad de Investigación, Hospital Universitario Santa Cristina, Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain.
Ana CortésCentro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide-CSIC, Sevilla, Spain.
Ana Victoria Lechuga-ViecoCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.
Pooja JadiyaCenter for Translational Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0003-4807-9304
Elisa NavarroInstituto Teófilo Hernando, Departamento de Farmacología y Terapéutica, Facultad de Medicina, Universidad Autónoma de Madrid (UAM), Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain.
Esther ParadaUnidad de Investigación, Hospital Universitario Santa Cristina, Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain.
Alejandra Palomino-AntolínUnidad de Investigación, Hospital Universitario Santa Cristina, Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain.
Daniel TelloUnidad de Investigación, Hospital Universitario Santa Cristina, Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain.
Rebeca Acín-PérezCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.
Juan Carlos Rodríguez-AguileraCentro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide-CSIC, Sevilla, Spain.
Plácido NavasCentro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide-CSIC, Sevilla, Spain.ORCID http://orcid.org/0000-0002-4115-7966
Ángel CogolludoCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain.ORCID http://orcid.org/0000-0002-1382-1698
Iván López-MonteroDepartamento de Química Física, Universidad Complutense de Madrid (UCM), Instituto de Investigación Sanitaria Hospital "12 de Octubre" (imas12), Madrid, Spain.ORCID http://orcid.org/0000-0001-8131-6063
Álvaro Martínez-Del-PozoDepartamento de Bioquímica y Biología Molecular, Universidad Complutense de Madrid (UCM), Madrid, Spain.ORCID http://orcid.org/0000-0003-0043-5939
Javier EgeaUnidad de Investigación, Hospital Universitario Santa Cristina, Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain.ORCID http://orcid.org/0000-0003-4704-3019
Manuela G LópezInstituto Teófilo Hernando, Departamento de Farmacología y Terapéutica, Facultad de Medicina, Universidad Autónoma de Madrid (UAM), Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain.
John W ElrodCenter for Translational Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0003-3925-2224
Jesús Ruíz-CabelloCenter for Cooperative Research in Biomaterials (CIC biomaGUNE), Basque Research and Technology Alliance (BRTA), Donostia San Sebastián, Spain.
Anna BogdanovaRed Blood Cell Group, Institute of Veterinary Physiology, Vetsuisse Faculty and ZIHP, University of Zurich, Zurich, Switzerland.
José Antonio EnríquezCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain. jaenriquez@cnic.es.ORCID http://orcid.org/0000-0002-3671-2961
Antonio Martínez-RuizUnidad de Investigación, Hospital Universitario Santa Cristina, Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain. amartinezruiz@salud.madrid.org.ORCID http://orcid.org/0000-0001-5394-9824
Hospital Universitario Santa Cristina · ESHospital Universitario de La Princesa · ESUniversidad Complutense de Madrid · ESCentre for Biomedical Network Research on Rare Diseases · ESSpanish National Centre for Cardiovascular Research · ESTemple University · USCIC biomaGUNE · ESIkerbasque · ESUniversity of California, Los Angeles · USUniversity of Zurich · CH
Funding
Molecular composition of the mitochondrial calcium uniporter and cardiac pathophysiologyR01HL142271 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI ELROD, JOHN WILLIAM, HAJNOCZKY, GYORGY · 2018 to 2021
$3.0MMechanisms of mitochondrial calcium exchange in heart failureR01HL123966 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2014 to 2018
$2.3MMitochondria and metabolism in neurodegenerationRF1NS121379 · NINDS · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2021 to 2021
$2.3MNovel Molecular Mechanisms of Programmed NecrosisR01HL136954 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2017 to 2020
$1.6MNHLBI NIH HHS R01 HL123966NHLBI NIH HHS R01 HL136954NHLBI NIH HHS R01 HL142271NINDS NIH HHS RF1 NS121379
Abstract
All metazoans depend on the consumption of O
Indexed as
Electron TransportSecond Messenger SystemsAnimalsBreast NeoplasmsCalcium PhosphatesCell Line, TumorChemical PrecipitationHumansHypoxiaMaleMembrane FluidityMice, Inbred C57BLMitochondriaMitochondrial MembranesMitochondrial ProteinsOxidative Phosphorylationcalcium phosphateCalcium PhosphatesMitochondrial ProteinsReactive Oxygen SpeciesSLC8B1 protein, humanSodiumSodium-Calcium Exchanger
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.