ArticleNature2020
Mechanisms of stretch-mediated skin expansion at single-cell resolution.
Erratum issuedOpen access · greenAbstract read
In one paragraph
Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 110 papers.
0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed
9.3field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
110 citing papers in PubMed, 196 citations in OpenAlex.
- A randomized, controlled clinical trial of autologous stromal vascular fraction cells transplantation to promote mechanical stretch-induced skin regeneration.Stem cell research & therapy · 2021Trial
- Sexual dimorphism in epidermal stem cell dynamics.Nature · 2026Article
- LGR5-positive fibroblasts orchestrate skin mechanoadaptation through JAK1 modulation.Nature communications · 2026Article
- Noncircadian BMAL1-YAP activity amplifies persistent inflammation in aged epidermis.Nature aging · 2026Article
- A stretch-responsive fibroblast program promotes epidermal stem cell self-renewal during skin expansion.Nature communications · 2026Article
- 4D-printed adaptive hydrogel tissue expanders for ear and breast reconstruction.Nature biomedical engineering · 2026Article
- Strategy based on liquid crystal elastomer active tensile to accelerate bone repair: Mechanistic analysis of LAMB1-ITGB4 mediated PI3K-AKT signaling.Materials today. Bio · 2026Article
- Cell proliferation and differentiation during epidermis renewal.Journal of Zhejiang University. Science. B · 2026Review
- Integrin-Binding Matricellular Protein Fibulin-5 Maintains Epidermal Stem Cell Heterogeneity During Skin Aging.Aging cell · 2026Article
- Essential Role of Integrin-Linked Kinase in Keratinocyte Responses to Mechanical Strain.International journal of molecular sciences · 2026Article
- Stress vesicles link epidermal mechanotransduction to stem cell differentiation.Nature communications · 2026Article
- SOX2 confers tumour permissiveness in a specific skin progenitor population.Nature communications · 2026Article
- Vascular endothelial cells as signaling niches for epithelial stem cells in the skin.Frontiers in cell and developmental biology · 2026Review
- Cell biomechanics on muscle atrophy: from intricate mechanisms to therapeutic frontiers.Annals of medicine · 2025Review
- How skin achieves mechano-resistance for land movement: the critical role of ER sensing.Cell regeneration (London, England) · 2025Article
- Mechanical Stretch-Induced Interlayer Coordination between MMP2 and COL17A1 Exacerbates Regenerative Exhaustion in Skin.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Mechanically Active Hydrogel for Healing Intestinal Fistulas through the YAP-Mediated Mechanosensitization of Intestinal Epithelial Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Mechanical control of histone serotonylation initiates neural crest migrationbioRxiv : the preprint server for biology · 2025Article
- Mechanical control of cell fate decisions in the skin epidermis.Nature communications · 2025Article
- Molecular and mechanical signatures contributing to mouse epidermal differentiation and barrier formation.eLife · 2025Article
50 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
17 authors at 5 institutions in 2 countries.
Mariaceleste AragonaLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles, Brussels, Belgium.
Alejandro SifrimDepartment of Human Genetics, University of Leuven, KU Leuven, Leuven, Belgium.
Milan MalfaitLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles, Brussels, Belgium.ORCID http://orcid.org/0000-0001-9144-3701
Yura SongLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles, Brussels, Belgium.ORCID http://orcid.org/0000-0002-1173-9172
Jens Van HerckDepartment of Human Genetics, University of Leuven, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-1291-4462
Sophie DekoninckLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles, Brussels, Belgium.
Souhir GargouriLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles, Brussels, Belgium.
Gaëlle LapougeLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles, Brussels, Belgium.
Benjamin SwedlundLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles, Brussels, Belgium.ORCID http://orcid.org/0000-0002-8264-9342
Christine DuboisLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles, Brussels, Belgium.
Pieter BaatsenElectron Microscopy Platform of VIB Bio Imaging Core, Leuven, Belgium.
Katlijn VintsElectron Microscopy Platform of VIB Bio Imaging Core, Leuven, Belgium.
Seungmin HanThe Wellcome Trust-Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.
Fadel TissirUniversité Catholique de Louvain, Institute of Neuroscience, Developmental Neurobiology, Brussels, Belgium.ORCID http://orcid.org/0000-0002-9292-6622
Thierry VoetDepartment of Human Genetics, University of Leuven, KU Leuven, Leuven, Belgium.
Benjamin D SimonsThe Wellcome Trust-Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK. bds10@cam.ac.uk.ORCID http://orcid.org/0000-0002-3875-7071
Cédric BlanpainLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles, Brussels, Belgium. cedric.blanpain@ulb.ac.be.ORCID http://orcid.org/0000-0002-4028-4322
Université Libre de Bruxelles · BEWellcome Sanger Institute · GBVIB-KU Leuven Center for Microbiology · BEWellcome/MRC Cambridge Stem Cell Institute · GBUCLouvain · BE
Funding
European Research Council 616333Medical Research Council MC_PC_12009Medical Research Council MC_PC_17230Wellcome TrustWellcome Trust 092096Wellcome Trust 098357/Z/12/Z
Abstract
The ability of the skin to grow in response to stretching has been exploited in reconstructive surgery
Indexed as
Single-Cell AnalysisAdaptor Proteins, Signal TransducingAdherens JunctionsAnimalsBase SequenceCell Cycle ProteinsCell DifferentiationCell Self RenewalChromatinChromatin Assembly and DisassemblyClone CellsDisease Models, AnimalExtracellular Signal-Regulated MAP KinasesGene Regulatory NetworksHydrogelsMechanotransduction, CellularAdaptor Proteins, Signal TransducingCell Cycle ProteinsChromatinExtracellular Signal-Regulated MAP KinasesHydrogelsMitogen-Activated Protein Kinase KinasesMrtfa protein, mouseRNA, MessengerTrans-ActivatorsTranscription Factor AP-1Yap1 protein, mouseYAP-Signaling Proteins
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.