Evidence map›Paper›PMID 32727983›Full record

ArticleInternal medicine (Tokyo, Japan)2020

Retroperitoneal Metastasis, with Marked Fibrosis, of Lung Adenocarcinoma after Afatinib Treatment: An Autopsy Case Report.

Hiroki Ota, Tomohiro Ota, Eriko Narisawa, Hideyuki Chiba, Hiroshi Nakayama, Yoko Tsukumo, Atsuhiko Sakamoto, Naoko Honma

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hiroki OtaDepartment of Respiratory Medicine, Japanese Red Cross Society, Omori Red Cross Hospital, Japan.
Tomohiro OtaDepartment of Respiratory Medicine, Japanese Red Cross Society, Omori Red Cross Hospital, Japan.
Eriko NarisawaDepartment of Respiratory Medicine, Japanese Red Cross Society, Omori Red Cross Hospital, Japan.
Hideyuki ChibaDepartment of Gastroenterology, Japanese Red Cross Society, Omori Red Cross Hospital, Japan.
Hiroshi NakayamaDepartment of Surgery, Japanese Red Cross Society, Omori Red Cross Hospital, Japan.
Yoko TsukumoDepartment of Pathology, Japanese Red Cross Society, Omori Red Cross Hospital, Japan.
Atsuhiko SakamotoDepartment of Pathology, Japanese Red Cross Society, Omori Red Cross Hospital, Japan.
Naoko HonmaDepartment of Pathology, Toho University School of Medicine, Japan.
Japanese Red Cross Society, Japan · JPToho University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 73-year-old woman was admitted to our hospital for treatment of vomiting. Four months previously, she had been diagnosed with lung adenocarcinoma (cT3N3M1a stage IVA) and started receiving afatinib as first-line treatment. On admission, the primary tumor had shrunk, but abdominal computed tomography revealed a new retroperitoneal lesion causing duodenal obstruction and hydronephrosis. She underwent gastrojejunostomy, and a biopsy of the peritoneum revealed adenocarcinoma. She was treated with second-line chemotherapy but developed cerebral infarction and died 104 days after admission. An autopsy revealed marked fibrosis with scattered tumor cells in the retroperitoneum. The underlying mechanism of the metastasis is discussed.

Indexed as

Adenocarcinoma of LungLung NeoplasmsRetroperitoneal FibrosisRetroperitoneal NeoplasmsAfatinibAgedAutopsyErbB ReceptorsFemaleFibrosisHumansAfatinibErbB ReceptorsEGFR mutationhydronephrosislung adenocarcinomaretroperitoneal fibrosisretroperitoneal metastasistransformation

Identifiers

PMID32727983
PMCPMC7725614
OpenAlexW3045841253

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.