ArticleJournal of atherosclerosis and thrombosis2021
Body Mass Index and Mortality From Aortic Aneurysm and Dissection.
Article in Journal of atherosclerosis and thrombosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Adiposity and the risk of aortic dissection incidence and mortality: results from the UK Biobank, the J-SHC study and a meta-analysis of cohort studies.European journal of epidemiology · 2026Article
- Adiposity and the risk of aortic aneurysm: results from the UK Biobank, Japan-Specific Health Check-ups Study and a systematic review and meta-analysis of cohort studies.European journal of epidemiology · 2026Article
- Impact of body mass index on outcomes in acute type A aortic dissection.Frontiers in cardiovascular medicine · 2026Article
- Blood pressure, hypertension, and the risk of aortic aneurysm in the UK Biobank.BMC cardiovascular disorders · 2025Article
- Neighborhood Racial and Ethnic Segregation and Obesity: A Systematic Review.Journal of racial and ethnic health disparities · 2025Review
- The association of metabolic syndrome with aortic aneurysm: a two-sample Mendelian randomization study.European journal of medical research · 2025Article
- Poor sleep quality is a risk factor for adverse clinical outcomes in patients with acute aortic dissection: A prospective cohort study.Journal of sleep research · 2025Article
- Global trends and risk factors of aortic aneurysm mortality from 1990 to 2021: An analysis of the Global Burden of Disease Study 2021.Asian heart journal · 2025Article
- Predicting Thoracic Aortic Dissection in a Diverse Biobank Using a Polygenic Risk Score.JACC. Advances · 2025Article
- Impact of preoperative risk factors on 5-year survival after fenestrated/branched endovascular aortic repair.Journal of vascular surgery · 2025Article
- Preoperative leptin levels were associated with postoperative acute kidney injury in patients with acute type A aortic dissection.Renal failure · 2024Article
- Disparities in mortality rates from aortic aneurysm and dissection by country-level income status and sex.JTCVS open · 2024Article
- Article
- Obesity and acute type A aortic dissection: unraveling surgical outcomes through the lens of the upper hemisternotomy approach.Frontiers in cardiovascular medicine · 2024Article
- Obesity and the obesity paradox in abdominal aortic aneurysm.Frontiers in endocrinology · 2024Review
- A Body Shape Index and Aortic Disease-Related Mortality in Japanese General Population.Journal of atherosclerosis and thrombosis · 2023Article
- Smoking Cessation and Mortality from Aortic Dissection and Aneurysm: Findings from the Japan Collaborative Cohort (JACC) Study.Journal of atherosclerosis and thrombosis · 2023Article
- Association of Physical Activity with Aortic Disease in Japanese Men and Women: The Japan Collaborative Cohort Study.Journal of atherosclerosis and thrombosis · 2023Article
- Distinct Mechanisms of β-Arrestin-Biased Agonist and Blocker of AT1R in Preventing Aortic Aneurysm and Associated Mortality.Hypertension (Dallas, Tex. : 1979) · 2023Article
- Body Mass Index and Mortality from Nonrheumatic Aortic Valve Disease among Japanese Men and Women.Journal of atherosclerosis and thrombosis · 2023Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsReports on an association between body mass index and aortic disease, which remains controversial. This study investigated the association between body mass index and mortality from aortic disease.
methodsWe conducted the Japan Collaborative Cohort Study, a prospective study of 103,972 Japanese men and women aged 40-79 years. Body mass index was calculated on the basis of self-reported height and weight, and the participants were followed up from 1988-89 through 2009. Sex-specific hazard ratios (95% confidence intervals) of mortality from aortic disease according to quintiles of body mass index were analyzed using the Cox proportional hazards model.
resultsDuring the median 18.8 years of follow-up, we documented 139 deaths due to aortic aneurysm (including 51 thoracic and 74 abdominal aortic aneurysms) and 134 deaths due to aortic dissection. We observed positive associations of body mass index with mortality from aortic aneurysm among men: the multivariable hazard ratios (95% confidence intervals) for highest versus lowest quintiles of body mass index were 4.48 (2.10-9.58), P for trend ＜0.0001 for aortic aneurysm; 6.52 (1.33-32.02), P=0.005 for thoracic aortic aneurysm; 3.81 (1.39-10.49), P=0.01 for abdominal aortic aneurysm; and 2.71 (1.59-4.62), P=0.001 for total aortic disease. No association was found for aortic dissection. Among ever-smokers (men ≥ 90%) but not never-smokers (women ≥ 84%), an association between body mass index and aortic disease mortality was observed regardless of sex, which may explain the sex difference (P for sex-interaction=0.046).
conclusionsWe found a positive association between body mass index and mortality from aortic aneurysm among Japanese men and smokers.
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