Evidence map›Paper›PMID 32727919›Full record

ArticleG3 (Bethesda, Md.)2020

Jian Liu, Laureline Mosser, Catherine Botanch, Jean-Marie François, Jean-Pascal Capp

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Strain background ofMicrobiology (Reading, England) · 2024
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jian LiuToulouse Biotechnology Institute, University of Toulouse, INSA, CNRS, INRAE, Toulouse, France.ORCID 0000-0002-4914-7025
Laureline MosserToulouse Biotechnology Institute, University of Toulouse, INSA, CNRS, INRAE, Toulouse, France.
Catherine BotanchToulouse Biotechnology Institute, University of Toulouse, INSA, CNRS, INRAE, Toulouse, France.
Jean-Marie FrançoisToulouse Biotechnology Institute, University of Toulouse, INSA, CNRS, INRAE, Toulouse, France.
Jean-Pascal CappToulouse Biotechnology Institute, University of Toulouse, INSA, CNRS, INRAE, Toulouse, France capp@insa-toulouse.fr.ORCID 0000-0002-6470-079X
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FRCentre National de la Recherche Scientifique · FRInstitut National des Sciences Appliquées de Toulouse · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromatin structure clearly modulates gene expression noise, but the reverse influence has never been investigated, namely how the cell-to-cell expression heterogeneity of chromatin modifiers may generate variable rates of epigenetic modification. Sir2 is a well-characterized histone deacetylase of the Sirtuin family. It strongly influences chromatin silencing, especially at telomeres, subtelomeres and rDNA. This ability to influence epigenetic landscapes makes it a good model to study the largely unexplored interplay between gene expression noise and other epigenetic processes leading to phenotypic diversification. Here, we addressed this question by investigating whether noise in the expression of

Indexed as

Saccharomyces cerevisiae ProteinsSirtuinsEpigenesis, GeneticGene Expression Regulation, FungalSaccharomyces cerevisiaeSilent Information Regulator Proteins, Saccharomyces cerevisiaeSirtuin 2TelomereSaccharomyces cerevisiae ProteinsSilent Information Regulator Proteins, Saccharomyces cerevisiaeSIR2 protein, S cerevisiaeSirtuin 2SirtuinsURA3 protein, S cerevisiaeEpigeneticsgene expression noisesilencingSIR2viability

Identifiers

PMID32727919
PMCPMC7466964
OpenAlexW3045973739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.