ArticleScience translational medicine2020
Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy.
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Article in Science translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
75 citing papers in PubMed, 102 citations in OpenAlex.
- Generation of two homozygous iPSC lines carrying variants of uncertain significance in LMNA associated with cardiomyopathy.Stem cell research · 2026Article
- Weekend-free and robotics-compatible protocols for high-throughput human-induced pluripotent stem cell maintenance, amplification, and differentiation.Stem cells translational medicine · 2026Article
- Vascularized Cardiac Tissue Engineering: From Advances in Biofabrication to Translational Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Telomere shortening in laminopathic dilated cardiomyopathy.NPJ Regenerative medicine · 2026Article
- Article
- A case report with the progression from atrial fibrillation to complete AV block, heart failure and electrical storm.Journal of geriatric cardiology : JGC · 2026Article
- Immunosuppression Drugs Exhibit Differential Effects on Endothelial Cell Function.Journal of vascular research · 2026Article
- Multiscale profiling of tyrosine kinase inhibitor cardiotoxicity reveals mechanosensitive ion channel PIEZO1 as cardioprotective.Science translational medicine · 2025Article
- Nuclear envelope components in vascular mechanotransduction: emerging roles in vascular health and disease.Nucleus (Austin, Tex.) · 2025Review
- Generation of an induced pluripotent stem cell line from a patient with Varicose veins.Stem cell research · 2025Article
- Decoding long COVID-associated cardiovascular dysfunction: Mechanisms, models, and new approach methodologies.Journal of molecular and cellular cardiology · 2025Review
- Age-related microbiome metabolites alter RNA splicing and chromatin accessibility in the brain.bioRxiv : the preprint server for biology · 2025Article
- Cardiac fibrosis: from mechanisms and models to medicines.Trends in pharmacological sciences · 2025Review
- LMNA-related cardiomyopathy: From molecular pathology to cardiac gene therapy.Journal of advanced research · 2025Review
- Alternatives to animal testing are the future - it's time that journals, funders and scientists embrace them.Nature · 2025Article
- Lamin: guardian against DNA damage by transcription stress.Cardiovascular research · 2025Article
- Generation of induced pluripotent stem cell line from a patient with long COVID.Stem cell research · 2025Article
- Engineering aortic valves via transdifferentiating fibroblasts into valvular endothelial cells without using viruses or iPS cells.Bioactive materials · 2025Article
- Endothelial IGFBP6 suppresses vascular inflammation and atherosclerosis.Nature cardiovascular research · 2025Article
- Stem cells in the treatment of myocardial injury-induced cardiomyopathy: mechanisms and efficient utilization strategies.Frontiers in pharmacology · 2025Review
15 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
17 authors at 2 institutions in 1 country.
Nazish SayedStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. joewu@stanford.edu sayedns@stanford.edu.ORCID 0000-0002-8229-721X
Chun LiuStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-8242-3896
Mohamed AmeenStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Farhan HimmatiStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Joe Z ZhangStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Saereh KhanamiriStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Jan-Renier MoonenStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-0361-824X
Alexa WnorowskiStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-1652-4728
Linling ChengStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0001-7585-1270
June-Wha RheeStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-7044-2985
Sadhana GaddamDepartment of Dermatology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0001-6477-0483
Kevin C WangDepartment of Dermatology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-5305-6791
Karim SallamStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Jack H BoydStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-3020-5280
Y Joseph WooStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-2506-492X
Marlene RabinovitchStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Joseph C WuStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. joewu@stanford.edu sayedns@stanford.edu.ORCID 0000-0002-6068-8041
Cardiovascular Institute of the South · USStanford University · US
Funding
Elucidating Mechanism of Cardiac Fibrosis with Cell Village of Pooled Human iPSCsR01HL130020 · NHLBI · STANFORD UNIVERSITY · PI Ronglih Liao, MARK MERCOLA · 2016 to 2026
$7.3MHuman Induced Pluripotent Stem Cells for Cardiovascular Disease ModelingR01HL113006 · NHLBI · STANFORD UNIVERSITY · PI WU, JOSEPH C. · 2012 to 2025
$6.8MHuman iPSCs for Elucidating Intercellular Crosstalk Signaling in Dilated CardiomyopathyR01HL141371 · NHLBI · STANFORD UNIVERSITY · PI WONG, WING H., WU, JOSEPH C. · 2018 to 2025
$6.2MModeling Tyrosine Kinase Inhibitor-Induced Vascular Dysfunction Using Human iPSCsR01HL141851 · NHLBI · STANFORD UNIVERSITY · PI WONG, WING H., WU, JOSEPH C. · 2018 to 2025
$5.7MGenome Editing of Human iPSCs to Study Inherited Hypertrophic CardiomyopathyR01HL126527 · NHLBI · STANFORD UNIVERSITY · PI QI, LEI STANLEY, WU, JOSEPH C. · 2015 to 2022
$5.4MModeling Susceptibility to Chemotherapy-Induced Cardiotoxicity Using Human iPSCsR01HL123968 · NHLBI · STANFORD UNIVERSITY · PI QUERTERMOUS, THOMAS, WU, JOSEPH C. · 2014 to 2021
$4.8MModeling Endothelial Dysfunction in LMNA-related Dilated CardiomyopathyK01HL135455 · NHLBI · STANFORD UNIVERSITY · PI SAYED, NAZISH · 2017 to 2021
$828kAmerican Heart Association-American Stroke Association 13SDG17340025NHLBI NIH HHS K01 HL135455NHLBI NIH HHS R01 HL113006NHLBI NIH HHS R01 HL123968NHLBI NIH HHS R01 HL126527NHLBI NIH HHS R01 HL130020NHLBI NIH HHS R01 HL141371NHLBI NIH HHS R01 HL141851
Abstract
Mutations in
Indexed as
Cardiomyopathy, DilatedInduced Pluripotent Stem CellsEndothelial CellsHumansLamin Type ALovastatinLamin Type ALMNA protein, humanLovastatin
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.