Evidence map›Paper›PMID 32727881›Full record

ArticleJournal of virology2020

Human Nasal Turbinate Tissues in Organ Culture as a Model for Human Cytomegalovirus Infection at the Mucosal Entry Site.

Or Alfi, Ido From, Arkadi Yakirevitch, Michael Drendel, Michael Wolf, Karen Meir, Zichria Zakay-Rones, Yuval Nevo, Sharona Elgavish, Ophir Ilan and 8 more

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Human Nasal and Lung Tissues InfectedJournal of virology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 2 countries.

Or Alfi *Clinical Virology Unit, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Ido From *Clinical Virology Unit, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Arkadi YakirevitchDepartment of Otolaryngology-Head and Neck Surgery, Sheba Medical Center, Tel Hashomer, Israel.
Michael DrendelDepartment of Otolaryngology-Head and Neck Surgery, Sheba Medical Center, Tel Hashomer, Israel.
Michael WolfDepartment of Otolaryngology-Head and Neck Surgery, Sheba Medical Center, Tel Hashomer, Israel.
Karen MeirDepartment of Pathology, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Zichria Zakay-RonesDepartment of Biochemistry, IMRIC, The Hebrew University Faculty of Medicine, Jerusalem, Israel.
Yuval NevoBioinformatics Unit of the I-CORE Computation Center, The Hebrew University and Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Sharona ElgavishBioinformatics Unit of the I-CORE Computation Center, The Hebrew University and Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Ophir IlanDepartment of Biochemistry, IMRIC, The Hebrew University Faculty of Medicine, Jerusalem, Israel.
Yiska WeisblumClinical Virology Unit, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Shay TayebDepartment of Biochemistry, IMRIC, The Hebrew University Faculty of Medicine, Jerusalem, Israel.
Menachem GrossDepartment of Otolaryngology/Head and Neck Surgery, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Wayne JonasSamueli Institute, Alexandria, Virginia, USA.
John IvesSamueli Institute, Alexandria, Virginia, USA.
Menachem OberbaumThe Center for Integrative Complementary Medicine, Shaare Zedek Medical Center, Jerusalem, Israel.
Amos PanetDepartment of Biochemistry, IMRIC, The Hebrew University Faculty of Medicine, Jerusalem, Israel.
Dana G WolfClinical Virology Unit, Hadassah Hebrew University Medical Center, Jerusalem, Israel dana.wolf@ekmd.huji.ac.il.
Hebrew University of Jerusalem · ILHadassah Medical Center · ILSamueli Institute · USSheba Medical Center · ILHadassah Academic College · ILShaare Zedek Medical Center · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The initial events of viral infection at the primary mucosal entry site following horizontal person-to-person transmission have remained ill defined. Our limited understanding is further underscored by the absence of animal models in the case of human-restricted viruses, such as human cytomegalovirus (HCMV), a leading cause of congenital infection and a major pathogen in immunocompromised individuals. Here, we established a novel

Indexed as

Virus InternalizationCell LineCytomegalovirusCytomegalovirus InfectionsEndothelial CellsFemaleFibroblastsForeskinHumansImmunity, InnateInfectious Disease Transmission, VerticalMaleMucous MembraneOrgan Culture TechniquesPregnancyTurbinateshuman cytomegalovirusnasal turbinatesorgan cultureviral mucosal entry site

Identifiers

PMID32727881
PMCPMC7495380
OpenAlexW3045493046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.