Evidence map›Paper›PMID 32727857›Full record

ArticlemSphere2020

Identification of Simplified Microbial Communities That Inhibit Clostridioides difficile Infection through Dilution/Extinction.

Jennifer M Auchtung, Eva C Preisner, James Collins, Armando I Lerma, Robert A Britton

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.5field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Present and future of microbiome-targeting therapeutics.The Journal of clinical investigation · 2025
    Review
  6. Isolation, Characterization, and Epizootiology of Clostridioides cuniculi from Immunodeficient Mice with Enteric Disease.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  7. mSphere · 2025
    Article
  8. Review
  9. Review
  10. Journal of clinical medicine · 2023
    Review
  11. Frontiers in microbiology · 2023
    Review
  12. Article
  13. Article
  14. Gut community alterations associated withFrontiers in microbiology · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Microbial model communities: To understand complexity, harness the power of simplicity.Computational and structural biotechnology journal · 2020
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jennifer M AuchtungAlkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0003-3038-583X
Eva C PreisnerAlkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA.
James CollinsAlkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA.
Armando I LermaAlkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA.
Robert A BrittonAlkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA robert.britton@bcm.edu.ORCID 0000-0001-8983-9539
Baylor College of Medicine · USUniversity of Nebraska–Lincoln · US

Funding

Diet driven evolution of epidemic ribotypes of Clostridium difficileR01AI123278 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI BRITTON, ROBERT A · 2018 to 2022
$2.0M
Defined microbial communities for the treatment of recurrent C. difficile infectionR33AI121522 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI BRITTON, ROBERT A · 2018 to 2020
$1.4M
NIAID NIH HHS R01 AI123278NIAID NIH HHS R33 AI121522
6 · The paper itself

Abstract

The gastrointestinal microbiome plays an important role in limiting susceptibility to infection with

Indexed as

Gastrointestinal MicrobiomeAdultAnimalsClostridioides difficileFecal Microbiota TransplantationFecesFemaleHumansMaleMiceMicrobiological TechniquesMiddle AgedClostridioides difficilecolonization resistanceFMTmicrobiomesimplified communities

Identifiers

PMID32727857
PMCPMC7392540
OpenAlexW3045936375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.