Evidence map›Paper›PMID 32727851›Full record

ArticleThe Journal of biological chemistry2020

15-Keto-PGE

Suzu Endo, Akiko Suganami, Keijo Fukushima, Kanaho Senoo, Yumi Araki, John W Regan, Masato Mashimo, Yutaka Tamura, Hiromichi Fujino

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Unique/Rapid Feedback Mechanisms of PGDBioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  2. Article
  3. GPCR Biased Signaling in Metabolism.Handbook of experimental pharmacology · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. 15-keto-PGEiScience · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Suzu EndoDepartment of Pharmacology for Life Sciences, Graduate School of Pharmaceutical Sciences and Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan.
Akiko SuganamiDepartment of Bioinformatics, Graduate School of Medicine, Chiba University, Chiba, Japan.
Keijo FukushimaDepartment of Pharmacology for Life Sciences, Graduate School of Pharmaceutical Sciences and Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan.
Kanaho SenooDepartment of Pharmacology for Life Sciences, Graduate School of Pharmaceutical Sciences and Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan.
Yumi ArakiDepartment of Pharmacology for Life Sciences, Graduate School of Pharmaceutical Sciences and Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan.
John W ReganDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona, USA.
Masato MashimoLaboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto, Japan.
Yutaka TamuraDepartment of Bioinformatics, Graduate School of Medicine, Chiba University, Chiba, Japan. Electronic address: yutaka_tamura@faculty.chiba-u.jp.
Hiromichi FujinoDepartment of Pharmacology for Life Sciences, Graduate School of Pharmaceutical Sciences and Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan. Electronic address: hfujino@tokushima-u.ac.jp.
Tokushima University · JPChiba University · JPDoshisha Women's College of Liberal Arts · JPUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostaglandin E

Indexed as

Computer SimulationModels, BiologicalSignal TransductionDinoprostoneHEK293 CellsHumansInflammationReceptors, Prostaglandin E, EP2 SubtypeReceptors, Prostaglandin E, EP4 Subtype15-ketoprostaglandin E2DinoprostoneReceptors, Prostaglandin E, EP2 SubtypeReceptors, Prostaglandin E, EP4 Subtype15-keto-PGE2biased agonistbiased ligandbioinformaticscancer biologyEP2 prostanoid receptorsEP4 prostanoid receptorsG-protein–coupled receptor (GPCR)PGE2pharmacologyprostaglandinSchild regressionswitched agonistswitched ligand

Identifiers

PMID32727851
PMCPMC7504929
OpenAlexW3046915035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.