Evidence map›Paper›PMID 32727848›Full record

ArticleThe Journal of biological chemistry2020

Molecular determinants of release factor 2 for ArfA-mediated ribosome rescue.

Daisuke Kurita, Tatsuhiko Abo, Hyouta Himeno

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. A cascade of structural rearrangements positions peptide release factor 2 for polypeptide hydrolysis on the ribosome.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Seed color in lettuce is determined by the LsTT2, LsCHS, and Ls2OGD genes from the flavonoid biosynthesis pathway.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023
    Article
  5. Ribosome Rescue Pathways in Bacteria.Frontiers in microbiology · 2021
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Daisuke KuritaDepartment of Biochemistry and Molecular Biology, Faculty of Agriculture and Life Science, Hirosaki University, Hirosaki, Japan. Electronic address: dkurita@hirosaki-u.ac.jp.
Tatsuhiko AboGraduate School of Natural Science and Technology, Okayama University, Okayama, Japan.
Hyouta HimenoDepartment of Biochemistry and Molecular Biology, Faculty of Agriculture and Life Science, Hirosaki University, Hirosaki, Japan. Electronic address: himeno@hirosaki-u.ac.jp.
Hirosaki University · JPOkayama University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Translation termination in bacteria requires that the stop codon be recognized by release factor RF1 or RF2, leading to hydrolysis of the ester bond between the peptide and tRNA on the ribosome. As a consequence, normal termination cannot proceed if the translated mRNA lacks a stop codon. In

Indexed as

Peptide Chain Termination, TranslationalEscherichia coliEscherichia coli ProteinsPeptide Termination FactorsRibosomesRNA-Binding ProteinsArfA protein, E coliEscherichia coli ProteinsPeptide Termination FactorsprfA protein, E coliprfB protein, E coliRNA-Binding ProteinsArfApeptidyl-tRNA hydrolysisprotein synthesisRF2ribosomeribosome rescuestalled ribosomestop codon-independent terminationtranslationtranslation controltranslation release factor

Identifiers

PMID32727848
PMCPMC7504928
OpenAlexW3045640510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.