Evidence map›Paper›PMID 32727827›Full record

ArticleJournal of clinical microbiology2020

Application of Targeted Next-Generation Sequencing Assay on a Portable Sequencing Platform for Culture-Free Detection of Drug-Resistant Tuberculosis from Clinical Samples.

Andrea M Cabibbe, Andrea Spitaleri, Simone Battaglia, Rebecca E Colman, Anita Suresh, Swapna Uplekar, Timothy C Rodwell, Daniela M Cirillo

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 4 pooled it
8.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 4 syntheses or guidelines pooled it, 140 citations in OpenAlex.

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  13. Frontiers in veterinary science · 2026
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20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Andrea M CabibbeEmerging Bacterial Pathogens Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Andrea SpitaleriEmerging Bacterial Pathogens Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Simone BattagliaEmerging Bacterial Pathogens Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Rebecca E ColmanFoundation for Innovative New Diagnostics, Campus Biotech, Geneva, Switzerland.
Anita SureshFoundation for Innovative New Diagnostics, Campus Biotech, Geneva, Switzerland.
Swapna UplekarFoundation for Innovative New Diagnostics, Campus Biotech, Geneva, Switzerland.
Timothy C Rodwell *Foundation for Innovative New Diagnostics, Campus Biotech, Geneva, Switzerland.
Daniela M Cirillo *Emerging Bacterial Pathogens Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy cirillo.daniela@hsr.it.ORCID 0000-0001-6415-1535
FIND · CHVita-Salute San Raffaele University · IT

Funding

Culture-free next generation sequencing for rapid detection of drug-resistant tuberculosisR21AI135756 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RODWELL, TIMOTHY CHARLES · 2018 to 2019
$500k
NIAID NIH HHS R21 AI135756
6 · The paper itself

Abstract

Targeted next-generation sequencing (tNGS) has emerged as a comprehensive alternative to existing methods for drug susceptibility testing (DST) of

Indexed as

Mycobacterium tuberculosisTuberculosis, Multidrug-ResistantHigh-Throughput Nucleotide SequencingHumansMicrobial Sensitivity TestsSequence Analysis, DNAdirect testdrug-resistant tuberculosisnext-generation sequencingportable sequencerrapid drug susceptibility testing

Identifiers

PMID32727827
PMCPMC7512157
OpenAlexW3045604772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.