Evidence map›Paper›PMID 32727822›Full record

ArticleCancer prevention research (Philadelphia, Pa.)2020

Stakeholder Perspectives on Overcoming Barriers to Cascade Testing in Lynch Syndrome: A Qualitative Study.

Swetha Srinivasan, Heather Hampel, Jennifer Leeman, Amit Patel, Alanna Kulchak Rahm, Daniel S Reuland, Megan C Roberts

Open access · greenAbstract read
In one paragraph

Article in Cancer prevention research (Philadelphia, Pa.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
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  14. Young-onset colorectal cancer.Nature reviews. Disease primers · 2023
    Review
  15. A Focused Clinical Review of Lynch Syndrome.Cancer management and research · 2023
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Swetha SrinivasanDivision of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0002-8330-1751
Heather HampelDivision of Human Genetics, The Ohio State Comprehensive Cancer Center, Columbus, Ohio.ORCID 0000-0001-7558-9794
Jennifer LeemanSchool of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Amit PatelMedical Marketing Economics, Oxford, Mississippi.
Alanna Kulchak RahmGenomic Medicine Institute, Geisinger Health System, Danville, Pennsylvania.ORCID 0000-0003-2513-9298
Daniel S ReulandDivision of General Internal Medicine and Clinical Epidemiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Megan C RobertsDivision of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. megan.roberts@unc.edu.
University of North Carolina at Chapel Hill · USCancer Genetics (United States) · USGeisinger Health System · USUniversity of Mississippi · US

Funding

North Carolina Translational and Clinical Science Institute (NC TraCS) KL2KL2TR002490 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WEINBERGER, MORRIS · 2018 to 2022
$11.0M
NCATS NIH HHS KL2 TR002490
6 · The paper itself

Abstract

Cascade testing (i.e., genetic testing of family members of individuals with disease) among families affected by hereditary cancer disorders, such as Lynch syndrome, is suboptimal and thus represents a missed opportunity in cancer prevention. We aimed to fill a gap in the literature by exploring multilevel barriers and facilitators to the implementation of cascade testing for Lynch syndrome. We conducted semistructured, in-depth interviews guided by the Consolidated Framework for Implementation Research and the Integrated Behavioral Model among key stakeholders (

Indexed as

Health Knowledge, Attitudes, PracticePatient Acceptance of Health CareAdultAgedColorectal Neoplasms, Hereditary NonpolyposisEarly Detection of CancerFamilyFemaleFollow-Up StudiesGenetic TestingHealth PlanningHumansInterviews as TopicMaleMiddle AgedPatient Participation

Identifiers

PMID32727822
PMCPMC7718347
OpenAlexW3046105477

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.